[HTML][HTML] Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes

W Wang, X Jing, T Du, J Ren, X Liu, F Chen… - Free Radical Biology …, 2022 - Elsevier
… We aimed to explore the roles of iron overloading in the … the Pfirrmann grading and diagnosis
standard for lumbar modic … μM NAC antioxidant for 24 h, and levels of expression of matrix

Riding the tiger–physiological and pathological effects of superoxide and hydrogen peroxide generated in the mitochondrial matrix

MD Brand - Critical reviews in biochemistry and molecular biology, 2020 - Taylor & Francis
… by phosphorylation or acetylation, antioxidant status, and so on, … a role, using reducing
equivalents from matrix glutathione … expression, then it is caused by matrix superoxide and not by …

[HTML][HTML] Oxidative stress and natural antioxidants in osteoporosis: Novel preventive and therapeutic approaches

G Marcucci, V Domazetovic, C Nediani, J Ruzzolini… - Antioxidants, 2023 - mdpi.com
… The purpose of this review is to provide an overview of … synthesis of proteins related to osteoid
matrix formation, such as … ratio and the expression of factors involved in bone remodeling, …

[HTML][HTML] The role of zinc and copper in gynecological malignancies

K Michalczyk, A Cymbaluk-Płoska - Nutrients, 2020 - mdpi.com
… highlight their role as potential biomarkers for cancer diagnosis, … The role of the antioxidant
system is to protect against the … of matrix metalloproteinases is regulated through the function

[HTML][HTML] Oxidative stress and low-grade inflammation in polycystic ovary syndrome: controversies and new insights

A Mancini, C Bruno, E Vergani, C d'Abate… - International Journal of …, 2021 - mdpi.com
… The different criteria used for diagnosis can have … the role of GH-IGF-1 axis in the modulation
of antioxidant … OC is one of the most represented protein in the bone matrix. Interestingly, …

[HTML][HTML] The role of inflammation and myeloperoxidase-related oxidative stress in the pathogenesis of genetically triggered thoracic aortic aneurysms

C Malecki, BD Hambly, RW Jeremy… - International Journal of …, 2020 - mdpi.com
… Despite diagnostic advances, the detection of TAAs in their early stages is difficult, since …
expression of matrix metalloproteinases (MMPs), a family of proteinases that play a role in …

[HTML][HTML] Oxidative stress in Graves disease and Graves orbitopathy

G Lanzolla, C Marcocci, M Marinò - European Thyroid Journal, 2020 - etj.bioscientifica.com
term, even though its beneficial effects in the long term are still to be investigated. In addition
to selenium, a protective role of other antioxidant … the role of oxidative stress and antioxidant

[HTML][HTML] The role of oxidative stress in ovarian aging: a review

F Yan, Q Zhao, Y Li, Z Zheng, X Kong, C Shu… - Journal of ovarian …, 2022 - Springer
… We also explore the role of antioxidant therapies such as … and reduced expression levels
of mitochondrial-related genes (… stimulate the production of extracellular matrix (ECM) and the …

[HTML][HTML] The dietary antioxidant quercetin reduces hallmarks of bleomycin-induced lung fibrogenesis in mice

AW Boots, C Veith, C Albrecht, R Bartholome… - BMC Pulmonary …, 2020 - Springer
… (expression of extracellular matrix genes and histopathology), inflammation (pulmonary gene
expression and plasma levels of tumor necrosis factor-… not reach statistical significance (p = …

[HTML][HTML] The role of oxidative stress in the aging heart

LU Pagan, MJ Gomes, M Gatto, GAF Mota, K Okoshi… - Antioxidants, 2022 - mdpi.com
… Medical advances and the availability of diagnostic tools have … role in age-associated
cardiac remodeling by enhancing matrix metallopeptidase activation and the expression