[HTML][HTML] Neuroplasticity and the biological role of brain derived neurotrophic factor in the pathophysiology and management of depression

S Chakrapani, N Eskander, LA De Los Santos… - Cureus, 2020 - ncbi.nlm.nih.gov
… This hypothesis emphasizes that depression is a result of … neuronal loss, decreased
hippocampal neurogenesis and loss of … pathophysiology of depression but also in discovering …

Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications

AN Tartt, MB Mariani, R Hen, JJ Mann… - Molecular psychiatry, 2022 - nature.com
… subgranular zone (SGZ) niche are remnants of dentate neuroepithelium [92] and this same
population of progenitors exclusively contributes to hippocampal neurogenesis throughout …

Adult hippocampal neurogenesis in major depressive disorder and Alzheimer's disease

T Berger, H Lee, AH Young, D Aarsland… - Trends in molecular …, 2020 - cell.com
… open novel ways of treatment and prevention to improve patient healthcare. Here, we discuss
recent studies specifically on the role of human adult hippocampal neurogenesis (AHN) in …

[HTML][HTML] Is adult hippocampal neurogenesis really relevant for the treatment of psychiatric disorders?

M Carli, S Aringhieri, S Kolachalam… - Current …, 2021 - ncbi.nlm.nih.gov
Adult neurogenesis consists in the generation of newborn neurons from neural stem cells
taking place in the adult brain. In mammals, this process is limited to very few areas of the brain…

Neurogenesis in the adult hippocampus: history, regulation, and prospective roles

J Fares, Z Bou Diab, S Nabha… - International Journal of …, 2019 - Taylor & Francis
Purpose/Aim: This article explores current advancements in adult hippocampal neurogenesis
… However, abnormal adult neurogenesis leads to pathophysiological states. For instance, …

Hormonal regulation of hippocampal neurogenesis: Implications for depression and exercise

A Gheorghe, W Qiu, LAM Galea - Neuroendocrine regulation of behavior, 2019 - Springer
… steroid hormone modulation of neurogenesis in the hippocampus with specific emphasis on
… the possible role of neurogenesis in the etiology of depression and influencing treatment by …

The therapeutic potential of traditional Chinese medicine in depression: targeting adult hippocampal neurogenesis

L Feng, H Xing, K Zhang - Phytomedicine, 2022 - Elsevier
depression pathophysiologyrole of hippocampal neurogenesis in depression and illustrate
the targets and mechanisms of the antidepressant effect of TCM by regulating neurogenesis, …

[HTML][HTML] Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis

A Wu, J Zhang - Journal of Neuroinflammation, 2023 - Springer
… of the hippocampus is one of two niches for neurogenesis in … are fundamental regulators
of this neurogenesis process. The … This review summarizes the functions of the hippocampus

The role of adult hippocampal neurogenesis in brain health and disease

T Toda, SL Parylak, SB Linker, FH Gage - Molecular psychiatry, 2019 - nature.com
… stages of AD or the heterogeneous nature of AD pathology. In addition, all human AD studies
… variable effects of AD pathology on adult hippocampal neurogenesis depending on the …

[HTML][HTML] A Baldwin interpretation of adult hippocampal neurogenesis: from functional relevance to physiopathology

DN Abrous, M Koehl, M Lemoine - Molecular psychiatry, 2022 - nature.com
… In this review, we propose to understand hippocampal neurogenesis as the process … and
adult hippocampal neurogenesis is made. We propose that their functions are the constitution …