SERCA2a: a key protein in the Ca2+ cycle of the heart failure

L Zhihao, N Jingyu, L Lan, S Michael, G Rui, B Xiyun… - Heart failure …, 2020 - Springer
… Disorders of SR function lead to the dysfunction of Ca 2+ … conditions for the transient
increase of intracellular Ca 2+ . … improved cardiac function in dilated heart disease mice and …

Etiology-dependent impairment of diastolic cardiomyocyte calcium homeostasis in heart failure with preserved ejection fraction

M Frisk, C Le, X Shen, ÅT Røe, Y Hou, O Manfra… - … College of Cardiology, 2021 - jacc.org
dysfunction (reduced E/A) but maintained systolic function (… function in diabetic HFpEF
may also be linked to intracellular Na … By comparison, maintained or even augmented Ca 2+ …

Interrelationship between Alzheimer's disease and cardiac dysfunction: the brain–heart continuum?

M Yang, C Li, Y Zhang, J Ren - Acta biochimica et biophysica …, 2020 - academic.oup.com
Patients with atrial fibrillation, heart failure, and other cardiacdysfunction, including the
disturbance of intracellular Ca 2+ … and cardiac diseases, since Ca 2+ plays a detrimental role in …

… inotropy: a position paper of the Committees on Translational Research and Acute Heart Failure of the Heart Failure Association of the European Society of Cardiology

C Maack, T Eschenhagen, N Hamdani… - European heart …, 2019 - academic.oup.com
… systolic function putatively without elevating intracellular Ca 2+ . … dysfunction in patients
with HF and the mechanisms through which different inotropic agents improve cardiac function. …

Mechanisms of cardiac dysfunction in diabetic cardiomyopathy: molecular abnormalities and phenotypical variants

FR Prandi, I Evangelista, D Sergi, A Palazzuoli… - Heart Failure …, 2023 - Springer
… is an increase in intracellular calcium (Ca 2+ ) and a decrease in sarcoplasmic Ca 2+ uptake
[… Lastly, a key contributing role in development and progression of myocardial injury and LV …

Untangling the pathophysiologic link between coronary microvascular dysfunction and heart failure with preserved ejection fraction

A Sinha, H Rahman, A Webb, AM Shah… - European Heart …, 2021 - academic.oup.com
… of life, and increased risk of adverse cardiovascular outcomes. There is … In this review article,
we will discuss the mechanistic role … of intracellular calcium via the L-type calcium channels. …

[HTML][HTML] Enhancement of cardiac store operated calcium entry (SOCE) within novel intercalated disk microdomains in arrhythmic disease

IM Bonilla, AE Belevych, S Baine, A Stepanov… - Scientific reports, 2019 - nature.com
… that consisted of removal of extracellular Ca 2+ ([Ca 2+ ] O ), and … of cardiac SOCE and its
role in in health and disease. … CPVT is characterized by absence of structural heart disease 12,…

Ion channels and vascular diseases

J Cheng, J Wen, N Wang, C Wang, Q Xu… - … , and vascular biology, 2019 - Am Heart Assoc
Ca 2+ channels, a reduction in intracellular Ca 2dysfunction in coronary heart disease.
Furthermore, ion channels not only affect smooth muscle function but also play an important role

Diabetes mellitus, ischemic heart disease and arterial hypertension

NG Shukhratovna, SD Erkinovna, XM Suxrobovna… - Pedagog, 2022 - bestpublication.org
cardiovascular disease and, in particular, for ischemic heart … is determined by variation in
intracellular calcium values. As … the pathophysiological role of coronary artery and pancreas …

Zn2+-transporters ZIP7 and ZnT7 play important role in progression of cardiac dysfunction via affecting sarco (endo) plasmic reticulum-mitochondria coupling in …

E Tuncay, CV Bitirim, Y Olgar, A Durak, GA Rutter… - Mitochondrion, 2019 - Elsevier
heart under pathological conditions, similar to Ca 2 + muffling… pathophysiology of heart
dysfunction and heart failure as its … a dynamic role as an extracellular/intracellular signaling factor …