… promotes extracellular Ca 2+ influx into intracellular cytosol. … disease, peripheral vascular
disease and heart failure, is related to vascular changes featured by endothelial dysfunction, …

… defection, and abnormal cardiomyocyte calcium flux during I/R stress. … cardiac mitochondrial
redox homeostasis, the intracellular … the role of SIRT1 and SIRT3 in ischemic heart disease …

… such as obesity, diabetes and heart disease is considered. … It is completely active at normal
intracellular Ca 2+ levels [34]. … ischemic heart disease (CHD) and endothelial dysfunction …

… (CVDs), such as hypertension, atherosclerosis, and heart failure. Aging is the main risk … in
intracellular Ca 2+ levels, activation of NADPH oxidase signalling, mitochondrial dysfunction, …

… can be blocked by millimolar extracellular Cs + concentrations [… , ischemic cardiomyopathy,
and heart failure [43, 93]. … voltage clock to cardiac automaticity towards the Ca 2+ clock is a …

… It induces subtle changes in intracellular pathways … role in cardiac aging and that supplement
with exogenous secreted Klotho protects against cardiac remodeling and heart failure in …

… heart attack, malignant cardiac arrhythmias, thromboembolic … stress increases diastolic
intracellular calcium concentration, wall … vessel injury and cardiovascular dysfunction ( Figure 2 ). …

… premature calcific artery disease have been identified. According to the respective function
of … the cell, leading to increased intracellular P i levels and calcium phosphate accumulation. …

… artery disease (CAD) is one of the major cardiovascular diseases affecting the global human
population. This disease … The SMCs then start proliferation and production of extracellular …

… because they can improve cardiac function and reduce a … intractable heart failure, especially
in younger patients, are … in deregulation of intracellular calcium homeostasis and finally …