… Human T-cell lymphotropic virus type 1 (HTLV-1) is the first … a critical role in promoting cell
survival, preventing apoptosis, and … the functional role of RAF1 and SOS1 in HTLV-1 infection. …

… These proteins have crucial roles during HTLV-1 infection and are responsible for the viral
… Many drugs induce apoptosis in ATL cells that are infected with HTLV-1. Caspases, anti- and …

… mRNA) play a crucial role in the oncogenesis of HTLV-1. The structural … HBZ is a viral protein
encoded by HTLV-1 that has a … from apoptosis of these cells carrying infection of HTLV-1 …

… be a key factor for both viral expression and pathogenesis, … role in leukemogenesis by
promoting proliferation of HTLV-1-… -α also induces cell cycle arrest and apoptosis by degradation …

… its contributions to HTLV-1-mediated disease development. … HTLV-1 carriers in Japan
determined that risk factors for ATL … T-cell receptor signaling, and apoptosis (CD45 and CD43), are …

… , T-cell receptor signaling, and apoptosis [29], have been reported to be upregulated in
HTLV-1 infection and may play a role in VB formation [30] and viral transmission [31]. Similarly, …

… HTLV-1 is an oncogenic virus in culture and infected patients. … Thus, their role in HTLV-1
infected individuals remains … with IFN to induce cell cycle arrest and apoptosis of ATLL cells. …

… The interaction between the host and viral factors is a complex … functions are disorganized
due to an accumulation of viral … regulate the cell cycle and induce apoptosis. They act mainly …

… to HTLV-1 have been considered to play important roles in … elevated HTLV-1 proviral load
(PVL) is the main risk factor … -infected CD4 + T cells could cause apoptosis in surrounding …

… is the viral oncoprotein Tax. However, Tax protein is not … neddylation inhibition induces
apoptosis in HTLV-1-infected T … and survivin proteins that play a role in this process. Substrates of …