Marine anthraquinones: pharmacological and toxicological issues

G Greco, E Turrini, E Catanzaro, C Fimognari - Marine drugs, 2021 - mdpi.com
… from marine sources, we will focus on the anticancer activity … before, a pivotal role in SZ-685C-induced
apoptosis was the … , but instead a potent inhibitory activity against different protein …

Novel anthraquinone compounds as anticancer agents and their potential mechanism

W Tian, C Wang, D Li, H Hou - Future medicinal chemistry, 2020 - Taylor & Francis
… Although the anthraquinone-induced apoptosis mainly occurs … on the antitumor activity of
newly synthesized anthraquinone … novel anthraquinone-based metal complexes show strong

[HTML][HTML] Marine compounds targeting the PI3K/Akt signaling pathway in cancer therapy

J Wei, Z Gou, Y Wen, Q Luo, Z Huang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
… with strong antitumor and antibacterial activityapoptosis induction by blocking the activation
of Akt in human breast tumor cells, yet its protein target and mechanism of anticancer action

Anthraquinones and their analogues from marine-derived fungi: Chemistry and biological activities

S Hafez Ghoran, F Taktaz, SA Ayatollahi, A Kijjoa - Marine Drugs, 2022 - mdpi.com
… cyclization of the first ring and the size of the final product, PT … in their search for antitumor
compounds from marine-derived … Compound 181 showed potent activity against all the tested …

Anthraquinone: a promising scaffold for the discovery and development of therapeutic agents in cancer therapy

S Siddamurthi, G Gutti, S Jana, A Kumar… - Future medicinal …, 2020 - Taylor & Francis
… from the rhizome of giant knotweed is having potent antitumor activity, both in vitro and in
vivo… from marine echinoderm was reported to act as potential novel lead for antitumor activity by …

[PDF][PDF] An overview of the mechanisms of marine fungi-derived antiinflammatory and anti-tumor agents and their novel role in drug targeting

SS Ul Hassan, M Ishaq, W Zhang, HZ Jin - Curr. Pharm. Des, 2021 - researchgate.net
… antiinflammatory and anti-tumor activities with special focus … H1 displayed a potent antiinflammatory
activity by inhibition of … A marine anthraquinone derivative SZ-685C, isolated from …

An overview of the mechanisms of marine fungi-derived anti-inflammatory and anti-tumor agents and their novel role in drug targeting

S Shams ul Hassan, M Ishaq… - Current …, 2021 - ingentaconnect.com
… antiinflammatory and anti-tumor activities with special focus … H1 displayed a potent antiinflammatory
activity by inhibition of … A marine anthraquinone derivative SZ-685C, isolated from …

Potential role of Marine Bioactive Compounds in cancer signaling pathways: A review

S Manoharan, E Perumal - European Journal of Pharmacology, 2022 - Elsevier
… integrating data from several marine anticancer research. Here, … apoptosis in cancer by
MBCs. Both intrinsic and extrinsic apoptosis is upregulated by compounds derived from marine

Bioactivities and structure–activity relationships of natural tetrahydroanthraquinone compounds: a review

S Feng, W Wang - Frontiers in Pharmacology, 2020 - frontiersin.org
… In addition, SZ-685C was reported to induce apoptosis in primary … Anthraquinones exhibited
potent antitumor effect, while they also … from marine fungi and plants. Some pharmacological …

Fungal Quinones: Benzo-, Naphtho-, and Anthraquinones

V López, F Les - Natural Secondary Metabolites: From Nature, Through …, 2023 - Springer
… Many of these compounds are also present in marine fungi associated … The potential antitumor
activity of these molecules is in … This anthraquinone is a potent stimulator of mitochondrial …