… According to the Centers for Disease Control and Prevention (CDC), a two-tier methodology
should be used in the serologic testing of Lyme disease [17]. As per CDC recommendations…

… latest Lyme borreliosis research and resulting treatment options. The development of safe
and effective vaccines against Lyme borreliosis … of a vaccine. Overall this might result in less …

… Vaccination for Lyme borreliosis should be considered for … or travel to regions with emerging
or endemic Lyme disease. … of immunogenicity, and the lipidated recombinant OspA-only …

… enable rapid identification and discovery of novel/potential vaccine antigens. (2) …
immunogenicity is a desirable vaccine attribute that potentially translates to protectivity against …

… In the realm of prevention, vaccines for Lyme borreliosis are … vaccine candidate that
combines the six most common OspA … Overall, the multivalent mRNA vaccine demonstrated …

… II trials to investigate immunogenicity, safety, tolerability, and … to developing effective vaccines
against Lyme Borreliosis (LB) … against LB that are based on outer surface protein A (OspA). …

… -OspA vaccine compared to those immunized with Recombitek, the canine Lyme disease
vaccine … This construct differs structurally from some Hpf constructs in that it is multivalent. The …

… in 1998 for protection against Lyme disease. However, was … coli and subsequently, their
immunogenicity and efficacy … vaccine candidates and the creation of a multivalent vaccine …

… Additionally, ferritin fusions have been investigated for enhancing the immunogenicity of
gonococcal MtrE [20] and Borrelia burgdorferi OspA [21] and a variety of nanoparticles has …

… ; the vaccines utilized a novel mode of action by stimulating human antibodies to OspA, …
results showing both a favorable safety profile and high immunogenicity across all tested age …