Schwann cell development: From neural crest to myelin sheath

AN Muppirala, LE Limbach, EF Bradford… - … : Developmental …, 2021 - Wiley Online Library
… Vertebrate nervous system function requires glial cells, including myelinating glia that …
crest-derived glial cells known as Schwann cells (SCs) generate myelin by encompassing and …

Development and in vitro differentiation of Schwann cells

SJ Hörner, N Couturier, DC Gueiber, M Hafner… - Cells, 2022 - mdpi.com
Myelinating Schwann cells develop through a further intermediate state… Schwann cell
lineages. This revealed that immature Schwann cells develop into four terminally differentiated cell

Cellular signal-regulated schwann cell myelination and remyelination

T Torii, Y Miyamoto, J Yamauchi - Myelin: Basic and Clinical Advances, 2019 - Springer
… in early developmental stages of Schwann cells, Arf proteins likely to be key regulator for
Schwann cells development. … in Schwann cells associate with myelination in CNS and PNS. …

The cell of Schwann: An update

RM Gould, KR Jessen, R Mirsky, G Tennekoon - Myelin, 2023 - taylorfrancis.com
… This hypothesis is based on experiments indicating that axon-Schwann cell signals stimulate
Schwann cell development from their earliest appearance, eg, E16 in rat sciatic nerve, and …

Transcriptional control of myelination and remyelination

E Sock, M Wegner - Glia, 2019 - Wiley Online Library
differentiating Schwann cells impairs myelin formation, whereas loss in mature Schwann
cells disturbs myelin … Both proteins are coexpressed during Schwann cell development and …

Optogenetic stimulation promotes Schwann cell proliferation, differentiation, and myelination in vitro

K Jung, JH Park, SY Kim, NL Jeon, SR Cho, S Hyung - Scientific reports, 2019 - nature.com
differentiation and myelination of SCs in a coculture model of SC and motor neuron (MN)
cells… To investigate whether OS of SCs also affected the differentiation and myelination of SCs …

The role of chromatin remodeling complexes in Schwann cell development

F Fröb, M Wegner - Glia, 2020 - Wiley Online Library
Schwann cells into myelinating Schwann cells. Each myelinating Schwann cell forms a …
in lineage progression and differentiation of Schwann cells and will be the focus of this review. …

Transcriptome analysis of Schwann cells at various stages of myelination implicates chromatin regulator Sin3A in control of myelination identity

B Zhang, W Su, J Hu, J Xu, P Askar, S Bao, S Zhou… - Neuroscience …, 2022 - Springer
… While the formation of myelin by Schwann cells (SCs) is … of the SC lineage through myelination
require further elucidation. … at various stages of myelination, and multilevel bioinformatic …

Schwann cell interactions during the development of the peripheral nervous system

ER Wilson, G Della‐Flora Nunes… - Developmental …, 2021 - Wiley Online Library
… Neuregulin 1 type III (NRG1-III) is a key axonal molecule guiding Schwann cell
development and myelination. NRG1-III is produced by and expressed on axons in an amount …

Axonal contact as a determinant of oligodendrocyte and Schwann cell function

TJ Neuberger, GH De Vries - Myelin, 2023 - taylorfrancis.com
Schwann cells which regulate the production of the myelinSchwann cells up regulate their
expression of the myelin… , the Schwann cell which will go on to form a mature myelin sheath …