Functions and gene expression alterations of phospholipase C in gametes

M Yeste, A Delgado-Bermúdez, C Jones… - Phospholipases in …, 2023 - Elsevier
… capacitation nor acrosome exocytosis induced by calcium … found that secretory PLA2 Group
IID (sPLA(2)-IID) isoform, … , is involved in the progesterone-induced acrosome reaction and …

Lipophilic phthalic acid esters impair human sperm acrosomal reaction through the likely inhibition of phospholipase A2-signaling pathway

I Cosci, A Garolla, A Cabrelle, S Sut… - Biochemical …, 2022 - Elsevier
Acrosome reaction was then induced by incubating … A) Evaluation of progesterone (P4)-triggered
sperm acrosome … , was associated with a severe blunt of the A32187-induced AR; …

Proteomic analysis of sperm from fertile stallions and subfertile stallions due to impaired acrosomal exocytosis

C Hernández-Avilés, L Ramírez-Agámez… - Scientific reports, 2024 - nature.com
associated with the metabolism of lipids at the sperm membrane, particularly by the activation
of phospholipase A2 (… progesterone-induced AE 65 . In that study, the reduced rate of AE …

Participation of the inositol 1, 4, 5-trisphosphate-gated calcium channel in the zona pellucida-and progesterone-induced acrosome reaction and calcium influx in …

YY Li, YP Jia, LY Duan, KM Li - Asian journal of andrology, 2020 - journals.lww.com
… ZP still indicate ZP protein involvement in the acrosome reaction of human spermatozoa. …
forms of stimulus-activated exocytosis and secretion of the acrosomal contents are ultimately …

[PDF][PDF] Identification and Quantification of Sperm Head Plasma Membrane Proteins Associated with Male Fertility

M Imran - 2022 - harvest.usask.ca
… HPM’s sodium/potassium-ATPase (Na+⁄K+-ATPase) acts as a receptor, inducing capacitation
when … abutting the nucleus is the inner acrosomal membrane, while the outer acrosomal

Altered G-protein transduction protein gene expression in the testis of infertile patients with nonobstructive azoospermia

D Hashemi Karoii, H Azizi, T Skutella - DNA and Cell Biology, 2023 - liebertpub.com
Acrosomal exocytosis following capacitation is related to Rab2A … involved in this reaction
called the acrosomal reaction. Using previously described methods, capacitation was induced

[图书][B] Peroxiredoxin 6 Peroxidase and Ca2+-independent Phospholipase A2 activities are essential for male mouse fertility

EG Bumanlag - 2021 - search.proquest.com
… The post-acrosomal region of the sperm head also includes proteins involved in … incubated
with 5 μM progesterone for 30 min at 37ºC to induce the acrosome reaction. After incubation, …

Physiological role of reactive oxygen species in male reproduction

D Durairajanayagam - Oxidants, antioxidants and impact of the oxidative …, 2019 - Elsevier
Progesterone secreted by cumulus cells act as a vital cofactor in this exocytosis event. The
Phospholipase A2 along with guanosine triphosphate-binding proteins and Ca 2+ are part of …

Updating Phospholipase A2 Biology

M Murakami, H Sato, Y Taketomi - Biomolecules, 2020 - mdpi.com
… Global or macrophage-specific sPLA 2 -IID deficiency … phase of the progesterone-induced
acrosome reaction ex vivo [… 2 β deficiency induces liver fibrosis and intestinal atrophy involving

Quantitative phosphoproteomics analyses reveal the regulatory mechanisms related to frozen-thawed sperm capacitation and acrosome reaction in yak (Bos …

R Zhang, C Liang, X Guo, P Bao, J Pei, F Wu… - Frontiers in …, 2022 - frontiersin.org
… sequester molecules involved in regulating sperm mobility and exocytosis. Dephosphorylation
induced by progesterone promotes acrosomal exocytosis in mouse sperm. Biol. Reprod. …