Proton pump inhibitors prevent gastric antral ulcers induced by NSAIDs via activation of capsaicin-sensitive afferent nerves in mice
H Satoh, Y Akiba, T Urushidani - Digestive Diseases and Sciences, 2020 - Springer
… Indomethacin produced lesions selectively in the … and capsaicin on ulcer formation
were inhibited by ablation of CSANs, pretreatment with a capsaicin receptor antagonist (capsazepine/…
were inhibited by ablation of CSANs, pretreatment with a capsaicin receptor antagonist (capsazepine/…
[HTML][HTML] Beyond neuronal heat sensing: diversity of TRPV1 heat-capsaicin receptor-channel functions
YM Shuba - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
… of vagal and spinal afferent nerve fibers by capsaicin, acid, … , support by functional evidence
greatly increase their validity. … , whereas cell exposure to capsaicin induced Ca 2+ influx and …
greatly increase their validity. … , whereas cell exposure to capsaicin induced Ca 2+ influx and …
Dry eye sensitizes cool cells to capsaicin-induced changes in activity via TRPV1
A Hatta, M Kurose, C Sullivan… - Journal of …, 2019 - journals.physiology.org
… Capsaicin-induced changes were prevented by the application of the TRPV1 antagonist
capsazepine. … might reflect an increase in TRPV1 receptors in TRPM8-positive corneal cells, as …
capsazepine. … might reflect an increase in TRPV1 receptors in TRPM8-positive corneal cells, as …
Capsaicin and TRPV1 channels in the cardiovascular system: the role of inflammation
… known to exhibit antinociceptive properties by desensitizing … [56] provided evidence that
capsaicin-induced stimulation of … capsazepine or SB-366791 or inhibition of the CB2 receptor …
capsaicin-induced stimulation of … capsazepine or SB-366791 or inhibition of the CB2 receptor …
[HTML][HTML] The impact of TRPV1 on cancer pathogenesis and therapy: a systematic review
L Li, C Chen, C Chiang, T Xiao, Y Chen… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
… be inhibited by the antagonists capsazepine and I-RTX 97 . Capsaicin induced apoptosis in
… However, this report does not include direct evidence to show if the synergism was exerted …
… However, this report does not include direct evidence to show if the synergism was exerted …
Antinociceptive activities of a novel diarylpentanoid analogue, 2-benzoyl-6-(3-bromo-4-hydroxybenzylidene) cyclohexen-1-ol, and its possible mechanisms of action …
… any sedative action and no evidence of acute toxic effect was … Our current results demonstrated
the capsaicin-induced pain … of capsazepine, a selective capsaicin receptor antagonist. It …
the capsaicin-induced pain … of capsazepine, a selective capsaicin receptor antagonist. It …
[HTML][HTML] TRP channels in cancer pain
AS de Almeida, L de Barros Bernardes… - European journal of …, 2021 - Elsevier
… The antinociceptive effects of cannabinoid receptor subtypes … peppers), capsazepine (a
TRPV1 non-selective antagonist), … Furthermore, LPA can increase capsaicin-induced currents …
TRPV1 non-selective antagonist), … Furthermore, LPA can increase capsaicin-induced currents …
Effective suppression of Ih and INa caused by capsazepine, known to be a blocker of TRPV1 receptor
… A synthetic inhibitor of capsaicin-induced TRPV1 channel … Results from the current
experimental work provide evidence … not connected with its antagonistic effect on vanilloid …
experimental work provide evidence … not connected with its antagonistic effect on vanilloid …
Effect of Arbutus andrachne L. methanolic leaf extract on TRPV1 function: Experimental and molecular docking studies
… that the extract decreased capsaicin-induced cobalt (Co+2) … pocket of TRPV1 receptor
similar to capsazepine, indicating … produces antinociceptive activity involving TRPV1 receptors, …
similar to capsazepine, indicating … produces antinociceptive activity involving TRPV1 receptors, …
[PDF][PDF] 2ʹ, 3, 3, 5ʹ-Tetramethyl-4ʹ-nitro-2ʹH-1, 3ʹ-bipyrazole exerts antinociceptive effect using various nociception models
… the supraspinal and spinal biological properties of novel drugs, … capsaicin-induced and
glutamate-induced paw-licking tests. … produced by capsazepine, a well-known TRPV antagonist. …
glutamate-induced paw-licking tests. … produced by capsazepine, a well-known TRPV antagonist. …