The role of TRP ion channels in migraine and headache
… Here we review the preclinical and clinical evidence that … to capsaicin at the same
anatomical site results in a selective … a TRPA1-mediated spinal antinociception in mice [107]. …
anatomical site results in a selective … a TRPA1-mediated spinal antinociception in mice [107]. …
8-Shogaol derived from dietary ginger alleviated acute and inflammatory pain by targeting TRPV1
X Cheng, Y Ruan, J Dai, H Fan, J Ling, J Chen, W Lu… - Phytomedicine, 2024 - Elsevier
… To ascertain whether antinociceptive role of 8S depend on … TRPV1 antagonist capsazepine
(CPZ, 10 µM) or TRPA1 antagonist … (D) Representative traces show that capsaicin-induced …
(CPZ, 10 µM) or TRPA1 antagonist … (D) Representative traces show that capsaicin-induced …
[HTML][HTML] The endocannabinoid system as a therapeutic target in diabetic peripheral neuropathic pain: a review
AM Bagher - Journal of Microscopy and Ultrastructure, 2022 - journals.lww.com
… R in the spinal cord mediates cannabinoids’ antinociceptive … TRPV1 antagonist capsazepine
blocked capsaicin's effects.[ … evidence of the antinociceptive properties of selective CB 2 R …
blocked capsaicin's effects.[ … evidence of the antinociceptive properties of selective CB 2 R …
… L. Fruit Extract Prevents Chronic Constriction Injury-Induced Neuropathic Pain in Rats: In Silico and In Vivo Evidence of TRPV1 Receptor and Cytokine Inhibition
… capsazepine, a competitive antagonist [72, 73], of the TRPV1 … reverses the effect of
capsaicin-induced neuropathic pain in … EESTF provides an excellent antinociceptive effect. The …
capsaicin-induced neuropathic pain in … EESTF provides an excellent antinociceptive effect. The …
[HTML][HTML] Multifunctional TRPV1 ion channels in physiology and pathology with focus on the brain, vasculature, and some visceral systems
… blocked by TRPV1 antagonists capsazepine and AMG9810, … secretion, while capsaicin-induced
desensitization has been … cannabinoid receptors in peripheral antinociception and …
desensitization has been … cannabinoid receptors in peripheral antinociception and …
TRP channel cooperation for nociception: therapeutic opportunities
D Bamps, J Vriens, J de Hoon… - Annual Review of …, 2021 - annualreviews.org
… capsaicin-induced acute pain is utilized nowadays in, for example, … Following the discovery
of capsazepine (Supplemental … Relying on its encouraging antinociceptive effect and evident …
of capsazepine (Supplemental … Relying on its encouraging antinociceptive effect and evident …
A Series of Novel Esters of Capsaicin Analogues Catalyzed by Candida antarctica Lipases
T Diaz-Vidal, LC Rosales-Rivera… - Biotechnology and …, 2020 - Springer
… the first competitive capsaicin antagonist, capsazepine, was … (RTX), competes with capsazepine
in the spinal cord, sensory neurons … Some evidence point out the beneficial role of CO …
in the spinal cord, sensory neurons … Some evidence point out the beneficial role of CO …
Impact of TRP channels in Oral pathology and therapeutic targeting options: a narrative review
E Evangeliou, G Plemmenos… - Current Topics in …, 2023 - ingentaconnect.com
… CPZ (Capsazepine) administration. CPZ revoked the capsaicin-induced TRPV1 activation, …
Eucalyptol, an agent used for antinociception, has been further suggested to exert its effect …
Eucalyptol, an agent used for antinociception, has been further suggested to exert its effect …
Glabridin alleviates inflammation and nociception in rodents by activating BKCa channels and reducing NO levels
… -administered capsazepine (TRPV receptor antagonist; 50 µg/mL; 10 µL i.pl.) with capsaicin.…
evaluation of the possible involvement of spinal mechanisms in anti-nociception are the tail …
evaluation of the possible involvement of spinal mechanisms in anti-nociception are the tail …