[HTML][HTML] Dual effect of anandamide on spinal nociceptive transmission in control and inflammatory conditions
M Pontearso, J Slepicka, A Bhattacharyya… - Biomedicine & …, 2024 - Elsevier
… in the dorsal horn to the antinociception is suggested via the CB … All of these neurons showed
capsaicin-induced increase (>… Increasing evidence indicates that spontaneous and evoked …
capsaicin-induced increase (>… Increasing evidence indicates that spontaneous and evoked …
TARGETING TRPV1 SIGNALING PATHWAY THROUGH NATURAL PRODUCTS ININFLAMMATORY CANCER
R Aggarwal - Journal of Advanced Scientific Research, 2021 - sciensage.info
… by capsazepine, a TRPV1 blocker and a capsaicin antagonist [70]. … Capsaicin induced the
activation of AMPK (adenosine 5'-… where the major ones are anti-nociception, anti-allergic, anti-…
activation of AMPK (adenosine 5'-… where the major ones are anti-nociception, anti-allergic, anti-…
Eugenol induces potent vasorelaxation in uterine arteries from pregnant goats–A promising natural therapeutic agent for hypertensive disorders of pregnancy
SC Parija, H Jandhyam, BP Mohanty, P Parasar… - bioRxiv, 2020 - biorxiv.org
… , capsazepine (CAPZ) and Ruthenium Red (RR), respectively… RR reduced maximal
capsaicin-induced uterine artery vasorelaxation … These results are supported by evidence of …
capsaicin-induced uterine artery vasorelaxation … These results are supported by evidence of …
Transient receptor potential vanilloid 1: A potential therapeutic target for the treatment of osteoarthritis and rheumatoid arthritis
… Extensive evidence in recent years has established the … Moderate extracellular acidification
inhibits capsaicin-induced cell death … Capsazepine, a vanilloid receptor antagonist, inhibits …
inhibits capsaicin-induced cell death … Capsazepine, a vanilloid receptor antagonist, inhibits …
Unlocking the potential of TRPV1 based siRNA therapeutics for the treatment of chemotherapy-induced neuropathic pain
… vanilloid substances including capsaicin, resiniferatoxin, and … Furthermore, TRPV1 inhibitor
capsazepine supressed the … employed and confirmed the antinociceptive action of a TRPV1 …
capsazepine supressed the … employed and confirmed the antinociceptive action of a TRPV1 …
Transient receptor potential vanilloid (TRPV) channels: Basal properties and physiological potential
T Sasase, F Fatchiyah, T Ohta - General physiology …, 2022 - repository.kulib.kyoto-u.ac.jp
… Capsazepine is synthesized as a structural analog of the capsaicin molecule, and binds
to the channel pore region (… potential channels leading to multiple anti-nociception. Br. J. …
to the channel pore region (… potential channels leading to multiple anti-nociception. Br. J. …
Resilience to capsaicin-induced mitochondrial damage in trigeminal ganglion neurons
M Shibata, Y Kayama, T Takizawa, K Ibata… - Molecular …, 2020 - journals.sagepub.com
… (b) The effects of capsazepine (100 μM) and bafilomycin A 1 (… capsaicin-induced
antinociception include TRPV1 receptor … Accumulated evidence shows that capsaicin-induced …
antinociception include TRPV1 receptor … Accumulated evidence shows that capsaicin-induced …
A role for substance P and acid-sensing ion channel 1a in prolotherapy with dextrose-mediated analgesia in a mouse model of chronic muscle pain
… , capsaicin… selective antagonist capsazepine to test whether TRPV1 is involved in dextrose
prolotherapy. Combined injection with 50 μM capsazepine did not change the antinociceptive …
prolotherapy. Combined injection with 50 μM capsazepine did not change the antinociceptive …
[HTML][HTML] Samanea tubulosa Benth. (Fabaceae): Antinociceptive effect on acute pain in mice: K+ATP channel and opioid activity
TF Alixandre, RP Sousa, BS Gomes… - Anais da Academia …, 2022 - SciELO Brasil
… of the lesion to the central areas of the brain through the spinal … capsazepine and ruthenium
red on capsaicin-induced … , we used pharmacological antagonists capable of preventing …
red on capsaicin-induced … , we used pharmacological antagonists capable of preventing …
[HTML][HTML] A journey from molecule to physiology and in silico tools for drug discovery targeting the transient receptor potential vanilloid type 1 (TRPV1) channel
CA Amaya-Rodriguez, K Carvajal-Zamorano… - Frontiers in …, 2024 - frontiersin.org
… Capsazepine is a synthetic compound structurally similar to capsaicin and is a classic
antagonist … Evidence of the existence of structurally defined modules in thermoTRP channels …
antagonist … Evidence of the existence of structurally defined modules in thermoTRP channels …