The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson's disease

A Björklund, RA Barker - Brain, 2024 - academic.oup.com
… allowing the derivation of authentic basal forebrain cholinergic neurons from human pluripotent
Selective immunolesioning of the basal forebrain cholinergic system disrupts short-term

Disruption of basal forebrain cholinergic neurons after traumatic brain injury does not compromise environmental enrichment-mediated cognitive benefits

EH Moschonas, JB Leary, K Memarzadeh… - Brain research, 2021 - Elsevier
… that selective cholinergic lesions to the basal forebrain did … non-selective lesions to the basal
forebrain impaired reversal … following global basal forebrain cholinergic lesions attenuated …

Modulation of prefrontal cortex function by basal forebrain cholinergic and GABAergic neurons at the behavioral and molecular level

GV Beselia, NC Chkhikvishvili, MA Burjanadze… - …, 2021 - journals.lww.com
… to study the effects of selective immunolesions of cholinergic or gamma-aminobutyric … the
immunolesion of cholinergic NBM neurons impair spatial working memory, as well as long-term

Regulation of cholinergic basal forebrain development, connectivity, and function by neurotrophin receptors

Z Boskovic, S Meier, Y Wang, MR Milne… - Neuronal …, 2019 - portlandpress.com
… of basal forebrain neurons and their role in maintaining and modifying mature basal forebrain
… targets has sufficient specificity to provide functionally and spatially selective signalling. …

Removal of p75 Neurotrophin receptor expression from cholinergic basal forebrain neurons reduces amyloid-β plaque deposition and cognitive impairment in aged …

L Qian, MR Milne, S Shepheard, ML Rogers… - Molecular …, 2019 - Springer
… [1], with the selective death of cholinergic basal forebrain (cBF) neurons emerging as a
potential … In humans, cBF neuronal degeneration causes basal forebrain atrophy that can be …

A functional topography within the cholinergic basal forebrain for encoding sensory cues and behavioral reinforcement outcomes

B Robert, EY Kimchi, Y Watanabe, T Chakoma, M Jing… - Elife, 2021 - elifesciences.org
Basal forebrain cholinergic neurons (BFCNs) project throughout the cortex to regulate …
Although often treated as a monolithic structure, the basal forebrain features distinct connectivity …

Basal forebrain cholinergic neurons have specific characteristics during the perinatal period

N Lozovaya, A Moumen, C Hammond - Eneuro, 2024 - eneuro.org
Cholinergic neurons of the basal forebrain represent the main source of cholinergic innervation
of large parts of the neocortex and are involved in adults in the modulation of attention, …

Neurotoxic Effects, Mechanisms, and Outcome of 192 IgG-Saporin Lesions

L Petrosini, P De Bartolo, D Cutuli - Handbook of Neurotoxicity, 2021 - Springer
… 192 IgG-saporin selectively destroys basal forebrain cholinergic neurons that provide …
Selective immunolesioning of the basal forebrain cholinergic system disrupts short-term memory in …

[HTML][HTML] Neural processing in the primary auditory cortex following cholinergic lesions of the basal forebrain in ferrets

FR Nodal, ND Leach, P Keating, JC Dahmen, D Zhao… - Hearing Research, 2024 - Elsevier
… An example of an NB ACh — immunolesion case (B) and an example of a control case (C). …
much of the cholinergic input from the basal forebrain had been selectively eliminated. These …

Basal forebrain-dorsal hippocampus cholinergic circuit regulates olfactory associative learning

Y Zheng, S Tao, Y Liu, J Liu, L Sun, Y Zheng… - International journal of …, 2022 - mdpi.com
… loss in CA1 and the DG disrupts the learning in olfactory associative … suggested that selective
deletion of the cholinergic neuronal … showed that selective depletion of cholinergic neurons …