Safety and efficacy of the selective progesterone receptor modulator asoprisnil for heavy menstrual bleeding with uterine fibroids: pooled analysis of two 12-month …

EA Stewart, MP Diamond, ARW Williams… - Human …, 2019 - academic.oup.com
STUDY QUESTION Can asoprisnil, a selective progesterone receptor modulator, provide
clinically meaningful improvements in heavy menstrual bleeding (HMB) associated with …

[PDF][PDF] KEY POINTS IN FERTILITY PRESERVATION TREATMENT STRATEGIES DURING COVID-19 PANDEMIC. AN UPDATE ON PHARMACOLOGICAL …

VN Varlas, RG BORȘ, BA NĂSUI, M Mititelu… - Farmacia, 2021 - researchgate.net
Fertility preservation is urgent by definition, performed for … We performed a systematic search
on fertility preservation (FP) … in ovarian stimulation on fertility preservation studied in the last …

Vilaprisan, a new selective progesterone receptor modulator in uterine fibroid pharmacotherapy-will it really be a breakthrough?

M Ciebiera, SG Vitale, S Ferrero… - Current …, 2020 - ingentaconnect.com
women suffering from symptoms related to UFs [3, 4]. To date, only patients with symptomatic
… (GnRH-a) or selective progesterone receptor modulators (SPRMs) are currently considered …

[PDF][PDF] Role of selective progesterone receptor modulators in the treatment of symptomatic uterine fibroids

N Naresh, P Mani, L Yadav, N Singh - International Journal of …, 2020 - academia.edu
… The most commonly used progesterone receptor modulator is mifepristone (RU486). It …
progesterone receptors, minimally to oestrogen receptors and up regulates androgen receptors. It …

Vilaprisan. Progesterone receptor modulator, Treatment of uterine fibroids

F Barra, M Seca, S Ferrero - Drugs of the Future, 2019 - access.portico.org
… for the management of symptomatic UF; it includes … for women aiming to preserve their
fertility (13-15), whereas myomectomy is a more suitable and valid option for symptomatic women

The selective progesterone receptor modulator ulipristal acetate inhibits the activity of the glucocorticoid receptor

B Small, CEF Millard, EP Kisanga… - The Journal of …, 2020 - academic.oup.com
… The objective of this study was to evaluate the impact of the selective progesterone receptor
modulator ulipristal on glucocorticoid signaling in relevant human cell types. Therefore, we …

Progesterone signaling and uterine fibroid pathogenesis; molecular mechanisms and potential therapeutics

M Ali, M Ciebiera, S Vafaei, S Alkhrait, HY Chen… - Cells, 2023 - mdpi.com
… of utilizing selective progesterone receptor modulators (… further supports the role progesterone
plays in UF pathogenesis … , and uterine size in 42 women with symptomatic UFs [77]. After …

Fertility preservation in women with early-stage gynecologic cancer: optimizing oncologic and reproductive outcomes

JL Floyd, S Campbell, JA Rauh-Hain… - International Journal of …, 2021 - ijgc.bmj.com
Preservation of fertility should be discussed with premenopausal women with early-stage
gynecologic cancer shortly after diagnosis and, for women who desire to preserve fertility, …

[HTML][HTML] Fertility optimization in women with cancer: from preservation to contraception

AS de Melo, CTV de Paula, MAF Rufato… - JBRA Assisted …, 2019 - ncbi.nlm.nih.gov
women, the duration of ovulation induction with gonadotropins and/or selective estrogen
receptor modulators (… Since the time to complete the fertility preservation cycle in women has to …

Consider fertility-preserving medications when treating adenomyosis

ES Kim, T Nie - Drugs & Therapy Perspectives, 2024 - Springer
Selective progesterone receptor modulators [eg mifepristone and ulipristal acetate] can …
symptomatic adenomyosis, fertility-preserving medical options are available Consider progestins