Mechanisms of oral absorption improvement for insoluble drugs by the combination of phospholipid complex and SNEDDS

Y Tong, Q Zhang, W Shi, J Wang - Drug Delivery, 2019 - Taylor & Francis
drug named silybin was encapsulated into self-nanoemulsifying drug delivery system (…
–SNEDDS and elucidate its mechanisms to improve the oral absorption of SB. Using a dynamic in …

Pharmacokinetics and bioavailability enhancement of natural products

PS Phansalkar, Z Zhang, S Verenich… - Natural Products for …, 2020 - Springer
… Several formulation efforts have been made to enhance the oral bioavailability of curcumin,
especially nanoparticle formulations, lipid-based drug delivery systems, and coformulation …

Effect and mechanism of edible oil co-digestion on the bioaccessibility and bioavailability of ursolic acid

Y Liu, H Xia, S Guo, P Li, S Qin, M Shi, C Zeng - Food Chemistry, 2023 - Elsevier
absorption. The results indicate that the location of UA distribution in oil determines the ease
of UA release into … for the design of improving the bioavailability of hydrophobic compounds. …

Hypotensive effects of the triterpene oleanolic acid for cardiovascular prevention

A Sureda, M Monserrat-Mesquida… - Current Molecular …, 2021 - ingentaconnect.com
improvement of the bioavailability of OA [50]. Also, a self-microemulsifying drug delivery system
(… approximately 5-fold increase in the oral bioavailability of OA [51]. Another approach to …

Development of lipid-based gastroretentive delivery system for gentian extract by double emulsion–melt dispersion technique

J Mudrić, K Šavikin, L Đekić, S Pavlović, I Kurćubić… - Pharmaceutics, 2021 - mdpi.com
… It was reported that gentiopicrin and oleanolic acid were loaded simultaneously into … in a
slower release of curcumin from self-microemulsifying drug delivery systems incorporated in …

Novel antimicrobial activities of self-nanoemulsifying drug delivery system (SNEDDS) ethyl acetate fraction from Garcinia mangostana L. peels against …

L Pratiwi - Journal of Applied Pharmaceutical Science, 2021 - japsonline.com
… A self-microemulsifying drug delivery system (SNEDDS). Int J Pharm Pharm Sci, 2010; 4:29–…
and bioavailability evaluation of a self-nanoemulsified drug delivery system of oleanolic acid…

A Soluplus/Poloxamer 407-based self-nanoemulsifying drug delivery system for the weakly basic drug carvedilol to improve its bioavailability

H Han, Y Li, Z Peng, K Long, C Zheng, W Wang… - … , Biology and Medicine, 2020 - Elsevier
… implied that the oral absorption of CAR was greatly improved. … improved the oral absorption
and bioavailability of the drug … could effectively enhance the oral bioavailability and provide …

[PDF][PDF] Self-Emulsifying Drug Delivery System a Tool for Enhancement of Solubility: A Critical Review

TA Dhawale, SD Pande, MK Sonawane, AR Jambhale… - ykh.org.in
… In vitro evaluation of drug release from self microemulsifying drug delivery systems using
a … Preparation and evaluation of self microemulsifying drug delivery system containing …

[PDF][PDF] Self-Nano Emulsifying Drug Delivery Systems

ML Hamzah, HJ Kassab, LH Samein - J Med Pharm Allied Sci, 2022 - jmpas.com
… of self-microemulsifying drug delivery systems, (SMEDDS) for oral bioavailability
delivery system of oleanolic acid, AAPS Pharm Sci Tech, 10:172-182. 50. Khan AW, Kotta S, …

Lipid nanocarriers for delivery of poorly soluble and poorly permeable drugs

AB Kovačević - Nanopharmaceuticals, 2020 - Elsevier
Self-microemulsifying drug delivery systems (SMEDDSs) or microemulsion preconcentrates
are defined as physically stable isotropic mixtures of oils (up to 20%), surfactants (HLB > 11) …