… and management of sepsis. We deliberate on pathophysiological features and dogmas that
… rules governing host-response trajectories in sepsis. Rule one highlights that the amplitude …

… the truly sickest septic patients. Current estimates of the incidence of sepsis amount to 48.9
… herein provide a summary of current and emerging management strategies in adult sepsis. …

… Here, we review current knowledge of immune dysregulations in sepsis. We describe
mechanisms that contribute to (a return to) homeostasis during and after bacterial encounters, with …

… of sepsis can be a guidepost that points toward improved diagnostics and therapies. In this
review, we discuss recent … patterns, novel biomarkers in sepsis, immunity monitoring, and …

… section reviews the currently modified sepsis definition and pathophysiology of sepsis. For
… presented on current diagnostic and management practices, along with challenges thereof. …

… This article provides a summary of the most recent clinical evidence and professional …
review recent changes in the definitions and clinical guidelines for the treatment of sepsis. …

… As sepsis is a leading cause of global mortality that still lacks … to unravel the complexity of
sepsis through high-dimensional … teach us about sepsis, and highlight current trends and future …

… is a life-threatening condition that arises when the body’s response to an infection injures
its … the recent developments in our understanding of the hallmarks of sepsis pathogenesis (…

… and biological heterogeneity displayed by the individual septic patient. Indeed, clear proof …
account for the marked heterogeneity within the septic patient’s biological phenotype and thus …

… Assessment of global incidence and mortality of hospital-treated sepsis current estimates
and limitations. Am J Respir Crit Care Med 2016;193:259-72. 10.1164/rccm.201504-…