Effect of rituximab treatment on T and B cell subsets in lymph node biopsies of patients with rheumatoid arthritis
TH Ramwadhdoebe, LGM van Baarsen… - …, 2019 - academic.oup.com
… After treatment, there was incomplete depletion of LN B cells. There was a significant …
of the different B cell subsets after two rituximab infusions was changed in favour of IgD − …
of the different B cell subsets after two rituximab infusions was changed in favour of IgD − …
Effects of B-cell directed therapy on the preclinical stage of rheumatoid arthritis: the PRAIRI study
DM Gerlag, M Safy, KI Maijer, MW Tang… - … of the rheumatic …, 2019 - ard.bmj.com
… Indeed, treatment of patients with RA with depleting … clinical and serological biomarkers
with the arthritis hazard was … number of B cells was observed within 4 weeks after treatment in …
with the arthritis hazard was … number of B cells was observed within 4 weeks after treatment in …
Early restoration of immune and vascular phenotypes in systemic lupus erythematosus and rheumatoid arthritis patients after B cell depletion
C Pérez‐Sánchez, I Cecchi… - Journal of Cellular …, 2019 - Wiley Online Library
… In this study, we aimed to explore changes in serologic parameters … following B lymphocyte
depletion in RA and SLE patients, along with their effects on the activity of other immune cells …
depletion in RA and SLE patients, along with their effects on the activity of other immune cells …
IL-40: a new B cell-associated cytokine up-regulated in rheumatoid arthritis decreases following the rituximab therapy and correlates with disease activity …
A Navrátilová, L Andrés Cerezo, H Hulejová… - Frontiers in …, 2021 - frontiersin.org
… -40 in RA and its decrease following B cell depleting therapy. … imply its potential involvement
in RA development. Moreover, … B Cell Depletion Therapy on Serological Evidence of B Cell …
in RA development. Moreover, … B Cell Depletion Therapy on Serological Evidence of B Cell …
… rheumatoid factor and cytokine expression by immunostimulated peripheral blood lymphocytes from patients with rheumatoid arthritis: New insights into B-cell …
JM Davis III, CS Crowson, KL Knutson… - Clinical …, 2020 - Elsevier
… the following scenario based on the role of T-helper cells in … shown to effectively deplete
activated B cells, which could be … Therapeutic success with rituximab may be related in part to …
activated B cells, which could be … Therapeutic success with rituximab may be related in part to …
B cell depletion treatment decreases Th17 cells in patients with rheumatoid arthritis
CA Bounia, SNC Liossis - Clinical Immunology, 2021 - Elsevier
… changes in the numbers of peripheral Treg and Th17 cells. … circulating T cell subpopulations
before and after treatment with … suggest that B cell depletion in patients with RA significantly …
before and after treatment with … suggest that B cell depletion in patients with RA significantly …
B-cell depletion in Rheumatoid Arthritis: clinical, biochemical and synovial predictors of response
A Mahto - 2019 - qmro.qmul.ac.uk
… of therapies available to treat rheumatoid arthritis (RA), predicting response to therapy …
post-translational modifications can lead to loss of tolerance with subsequent asymptomatic …
post-translational modifications can lead to loss of tolerance with subsequent asymptomatic …
[HTML][HTML] Rituximab levels are associated with the B cell homeostasis but not with the clinical response in patients with rheumatoid arthritis
C Diaz-Torne, MÀ Ortiz, M Sarmiento… - … of Rheumatology, 2019 - ncbi.nlm.nih.gov
… B lymphocyte depletion levels on days 30 and 90 after the first … B-cell depletion therapy on
serological evidence of B-cell and plasmablast activation in patients with rheumatoid arthritis …
serological evidence of B-cell and plasmablast activation in patients with rheumatoid arthritis …
In rheumatoid arthritis, changes in autoantibody levels reflect intensity of immunosuppression, not subsequent treatment response
EC de Moel, VFAM Derksen, LA Trouw, H Bang… - Arthritis research & …, 2019 - Springer
… changes in autoantibody levels following treatment … diseases, these serological changes in
RA may hold promise as an … underlying the B cell autoimmune response in RA and its role in …
RA may hold promise as an … underlying the B cell autoimmune response in RA and its role in …
[HTML][HTML] … peripheral blood B cells in rheumatoid arthritis and relationship to anti-TNF treatment and response: randomized clinical trial for anti-TNF effects on B cells
…, J Barnard, K Callahan, A Coca, B Marston… - … & rheumatology …, 2022 - ncbi.nlm.nih.gov
… B cell depletion therapy further highlights the pathogenic significance of B cells in RA (5–7). …
pathways on human B cells remain unclear as careful longitudinal studies after anti-TNF …
pathways on human B cells remain unclear as careful longitudinal studies after anti-TNF …