Shared and unique immune alterations in pre-clinical autoimmunity
S Slight-Webb, RL Bourn, VM Holers… - Current opinion in …, 2019 - Elsevier
… of future seropositive RA. However, over one-third of RA patients are seronegative in early
… had upregulated type I and type II IFN-inducible genes, and like early RA patients, showed …
… had upregulated type I and type II IFN-inducible genes, and like early RA patients, showed …
Real‐World Treatment Effectiveness of Disease‐Modifying Antirheumatic Drugs by Serostatus Among Patients With Rheumatoid Arthritis
… seropositive and seronegative patients with RA are managed in a real-world setting and
provide data on the effectiveness of different biologic DMARDs (bDMARDs)/JAKi for RA … similar …
provide data on the effectiveness of different biologic DMARDs (bDMARDs)/JAKi for RA … similar …
Association of the serological status of rheumatoid arthritis patients with two circulating protein biomarkers: A useful tool for precision medicine strategies
C Ruiz-Romero, P Fernández-Puente… - Frontiers in …, 2022 - frontiersin.org
… a further classification of the RA seropositive patients into two novel … In this step, we analysed
the same 80 samples individually in … All of them were decreased in the double seronegative …
the same 80 samples individually in … All of them were decreased in the double seronegative …
Cytokines (IL-15, IL-21, and IFN-γ) in rheumatoid arthritis: association with positivity to autoantibodies (RF, anti-CCP, anti-MCV, and anti-PADI4) and clinical activity
IV Reyes-Pérez, PE Sánchez-Hernández… - Clinical …, 2019 - Springer
… /anti-MCV seropositive RA patients than in the other groups. The … serum levels in seronegative
and seropositive RA patients. a … with RA, which agrees with a study conducted in the same …
and seropositive RA patients. a … with RA, which agrees with a study conducted in the same …
'Non-criteria antiphospholipid antibodies': bridging the gap between seropositive and seronegative antiphospholipid syndrome
S Truglia, S Mancuso, A Capozzi, S Recalchi… - …, 2022 - academic.oup.com
… for the seronegative is the existence of different antigenic targets… cohort of SN-APS patients
is similar to that described in the Euro-… The same pathway of endothelial activation has been …
is similar to that described in the Euro-… The same pathway of endothelial activation has been …
Cellular and molecular diversity in Rheumatoid Arthritis
F Rivellese, C Pitzalis - Seminars in Immunology, 2021 - Elsevier
… of RA, it is plausible to hypothesize that different pathways … CI 0.12 to 0.84) in seropositive
vs seronegative patients [11]. … , today we know that the same mechanisms are not active in all …
vs seronegative patients [11]. … , today we know that the same mechanisms are not active in all …
Expansion of Alternative Autoantibodies Does Not Follow the Evolution of Anti–Citrullinated Protein Antibodies in Preclinical Rheumatoid Arthritis: An Analysis in At …
V Anaparti, I Smolik, X Meng, L O'Neil… - Arthritis & …, 2021 - Wiley Online Library
… , including asymptomatic, seronegative FDR, … -TPO positive (5,6). Based on our studies, it
was not possible to determine whether latent autoimmunity patterns in RA are similar to other …
was not possible to determine whether latent autoimmunity patterns in RA are similar to other …
Antibodies against carbamylated proteins: prevalence and associated disease characteristics in Belgian patients with rheumatoid arthritis or other rheumatic diseases
P Sidiras, D Spruyt, V Gangji, V Imbault… - Scandinavian journal …, 2021 - Taylor & Francis
… -CarP-positive RA subgroup than in anti-CarP-negative RA (p … cohort of patients with RA
and other rheumatic conditions, such … seronegative RA patients at risk of more severe disease. …
and other rheumatic conditions, such … seronegative RA patients at risk of more severe disease. …
Disordered antigens and epitope overlap between anti–citrullinated protein antibodies and rheumatoid factor in rheumatoid arthritis
… binding in seronegative and seropositive RA to identify novel … , similar to most studies
evaluating antibody binding in RA, in … in seronegative disease might suggest a different disease …
evaluating antibody binding in RA, in … in seronegative disease might suggest a different disease …
Methotrexate Reduces the Probability of Discontinuation of TNF Inhibitors in Seropositive Patients With Rheumatoid Arthritis. A Real-World Data Analysis
B Hernández-Breijo, CM Brenis… - Frontiers in …, 2021 - frontiersin.org
… of TNFi in seronegative and seropositive patients with RA. In … this difference was not found
for seronegative patients due to the fact that median TNFi survival time was statistically similar …
for seronegative patients due to the fact that median TNFi survival time was statistically similar …