The sex-specific effects of LPS on depressive-like behavior and oxidative stress in the hippocampus of the mouse

CE Millett, BE Phillips, EFH Saunders - Neuroscience, 2019 - Elsevier
… related to potential sex differences in inflammation-based … method, and data are presented
as a relative fold change with … We found altered gene expression in the hippocampus in both …

[HTML][HTML] Gestational diabetes triggers oxidative stress in hippocampus and cerebral cortex and cognitive behavior modifications in rat offspring: Age-and sex …

M Huerta-Cervantes, DJ Peña-Montes… - Nutrients, 2020 - mdpi.com
… female offspring in young and adult rats, we first evaluated ROS … to the lower anxiety level
presented in this group. However, … impact of oxidative stress and the inflammatory response to …

Sex differences in depressive-like behaviour may relate to imbalance of microglia activation in the hippocampus

LL Liu, JM Li, WJ Su, B Wang, CL Jiang - Brain, behavior, and immunity, 2019 - Elsevier
… about behavioural and neurochemical alterations, … provided a preliminary exploration to
the role of hippocampal microglia-related inflammation and BDNF in the pathogenesis of sex

Affective behavior shows sex differences in mid-adulthood rats following postnatal immune stimulation

I Berkiks, A Mesfioui, A Ouichou, R Nakache… - Neuroscience, 2019 - Elsevier
… between sex differences and LPS-induced alterations in behavior and associated oxidative
and … statement of ethical standards for manuscripts submitted to the journal neuroscience. …

[HTML][HTML] Sex-dependent effects of perinatal inflammation on the brain: implication for neuro-psychiatric disorders

M Ardalan, T Chumak, Z Vexler, C Mallard - International journal of …, 2019 - mdpi.com
… of how sex influences the inflammatory reactions that may … These alterations result in
numerous permanent sex-related … This mouse model has also provided evidence for a causal …

[HTML][HTML] Sex-specific effects of early life stress on brain mitochondrial function, monoamine levels and neuroinflammation

H González-Pardo, JL Arias, E Gómez-Lázaro… - Brain Sciences, 2020 - mdpi.com
altered mitochondrial function, including increased oxidative … and prefrontal cortex of male
rats, but not in female rats [78,79]. … their known anti-inflammatory effects could partially explain …

[HTML][HTML] Sex-specific hippocampal metabolic signatures at the onset of systemic inflammation with lipopolysaccharide in the APPswe/PS1dE9 mouse model of …

A Agostini, D Yuchun, B Li, DA Kendall… - Brain, behavior, and …, 2020 - Elsevier
… LPS administration rapidly altered hippocampal metabolism … their pro-inflammatory and
pro-oxidant metabolic signature … food and water, and were provided with nesting material and a …

Adolescent stress sensitizes the adult neuroimmune transcriptome and leads to sex-specific microglial and behavioral phenotypes

M Bekhbat, D Mukhara, MG Dozmorov… - …, 2021 - nature.com
sex would dictate differential induction of inflammation-related … and endocrine pathways
known to be altered by chronic … which could contribute to sex differences presented in the current …

Impact of sex differences and gender specificity on behavioral characteristics and pathophysiology of neurodegenerative disorders

MF Ullah, A Ahmad, SH Bhat, FM Abu-Duhier… - Neuroscience & …, 2019 - Elsevier
… , which has both a high metabolic rate and an increased sensitivity to oxidative damages, …
C57Bl/6 mice provided evidence of behavioral and epigenetic alterations being transmitted to …

Neurodegenerative disease: roles for sex, hormones, and oxidative stress

N Sumien, JT Cunningham, DL Davis… - …, 2021 - academic.oup.com
… of inflammation may play a key role in sex differences (28). Male and female mice have …
Intracellular nuclear receptors mediate genomic alteration of gene transcription by sex hormones…