… suppressor that has been shown to upregulate Atg7 and Beclin-1 and have … Astaxanthin
activated the Nrf2/HO-1 pathway to enhance … Shikonin attenuates acetaminophen-induced acute …

… both in acetaminophen-induced acute hepatitis model and … , mitochondrial dysfunction,
downregulation of inflammation and … For example, shikonin could attenuate DIH via inhibition of …

… study found that shikonin significantly attenuated LTA‑induced ALI. Following shikonin treatment,
… of neutrophil apoptosis is closely related to upregulated Mcl-1 and results in increased …

… that shikonin attenuates acetaminophen (APAP)-induced acute liver injury via inhibiting …
In the present study, we found that Airn was upregulated in CCl 4 - induced acute liver injury …

… , with different degrees of significant upregulation of acetic and butyric acid in the CG group
(p < 0.01) and butyric acid being significantly upregulated in the CG and CZ group (p < 0.01). …

… Our findings revealed a downregulation of FXR expression in APAP and APAP + ATB mice,
while an upregulation was observed in wolfberry, wolfberry + ATB, and NAC mice (Fig. 5A …

… with shikonin by suppressing apoptosis and 90 autophagy via … to protect against 111
acetaminophen-induced liver injury in mice … attenuate the lipid 260 accumulation in the liver [86]. …

… Similarly, we detected the up-regulation of IL-6 in the mice AILI model and observed
recruitment of neutrophils in liver. After IFP35-Ab treatment, the expression of related pro-…

… According to previous studies, DADS treatment ameliorates hepatotoxicity via downregulation
of … and our findings suggest that DADS could attenuate 1,3-DCP-induced hepatotoxicity. …

… under HG conditions and that Nrf2-HO-1 plays … attenuated cell apoptosis and oxidative
damage induced by HG in NRK-52E cells, and that the effect might be mediated through the Nrf2/…