… Astragaloside IV activates the NRF2 signalling pathway, thereby increasing GPX4 … SOD
activity, reduces MDA levels, upregulates GPX4 expression, downregulates ACSL4 expression, …

… Seaweed natural products modify the host inflammatory response via Nrf2 signaling and
alter … Shikonin attenuates acetaminophen-induced acute liver injury via inhibition of oxidative …

… inflammatory cytokines through an acute phase response in the liver. Following oxidative
stress, to maintain a cellular redox homeostasis, it is necessary to upregulate the expression …

… have been focused on CD44 and NRF2 genes. CD44 is a … Also, NRF2 is a transcription
factor whose activation under … that the occurrence of NRF2 rs6726395 increases the risk of …

… However, these three target genes were markedly upregulated in the jejunum (Figure 6D). …
6E) and ALP (Figure 6F) were considerably upregulated in the jejunum of the TC-F1 group …

… Among these genes, 1583 were found to be upregulated while 1392 were down-regulated.
Gene … Figure 7 ALA attenuated oxidative stress in rats after SCI (A) Three days after SCI, total …

… On the other hand, spleen tissues of LPS challenged mice treated by FX or IR and their
combination showed attenuated pathological changes comparable to that of control as revealed …

… It is worth mentioning that the three treatments could attenuated … ameliorated
acetaminopheninduced hepatic cytotoxicity via … Nrf2 promotes the development of brosis and …

Ethnopharmacological relevance The root of Angelica sinensis, has been commonly used
in gynecology for centuries, and is normally applied divided into different parts in various …

… superoxide dismutase activity through Keap1/Nrf2, AMPK/Nrf2, and … that naphthoquinone
shikonin extracted from shikonin could … in a dose dependent manner via a p53 mediated signal …