Molecular monitoring of patient response to painkiller drugs

P Ayuso, Y Macías, J Gómez-Tabales… - Expert Review of …, 2022 - Taylor & Francis
… have been focused on CD44 and NRF2 genes. CD44 is a … Also, NRF2 is a transcription
factor whose activation under … that the occurrence of NRF2 rs6726395 increases the risk of …

Progress on the extraction, separation, biological activity, and delivery of natural plant pigments

X Lu, W Li, Q Wang, J Wang, S Qin - Molecules, 2023 - mdpi.com
… superoxide dismutase activity through Keap1/Nrf2, AMPK/Nrf2, and … that naphthoquinone
shikonin extracted from shikonin could … in a dose dependent manner via a p53 mediated signal …

Role of leptin/STAT3 signaling and RIP-kinases in fucoxanthin influences on mice exposed to LPS and gamma radiation

MK Abdel-Rafei, NM Thabet, G El Tawel… - Toxin …, 2023 - Taylor & Francis
… On the other hand, spleen tissues of LPS challenged mice treated by FX or IR and their
combination showed attenuated pathological changes comparable to that of control as revealed …

The beneficial effect of α-lipoic acid on spinal cord injury repair in rats is mediated through inhibition of oxidative stress: A transcriptomic analysis

MM Bian, YM Xu, L Zhang, HZ Yan, JX Gao… - The Journal of Spinal …, 2024 - Taylor & Francis
… Among these genes, 1583 were found to be upregulated while 1392 were down-regulated.
Gene … Figure 7 ALA attenuated oxidative stress in rats after SCI (A) Three days after SCI, total …

Constitutive Androstane Receptor Agonist, TCPOBOP: Maternal Exposure Impairs the Growth and Development of Female Offspring in Mice

S Pan, Y Guo, W Yu, J Zhang, X Qiao, L Li… - International Journal of …, 2023 - mdpi.com
… However, these three target genes were markedly upregulated in the jejunum (Figure 6D). …
6E) and ALP (Figure 6F) were considerably upregulated in the jejunum of the TC-F1 group …

Strategy for treating MAFLD: Electroacupuncture alleviates hepatic steatosis and fibrosis by enhancing AMPK mediated glycolipid metabolism and autophagy in T2DM …

D Haoru, S Song, R Li, S Hu, S Zhuang, X Li, W Gao - 2024 - researchsquare.com
… It is worth mentioning that the three treatments could attenuated … ameliorated
acetaminopheninduced hepatic cytotoxicity viaNrf2 promotes the development of brosis and …

Sodium alginate combined with oxymatrine ameliorates CCl4-induced chemical hepatic fibrosis in mice

C He, W Wang, G Wei, Y Wang, Y Wei, J Wang… - International …, 2023 - Elsevier
… liver tissues was detected using immunohistochemical staining and western blotting. α-SMA
upregulation is a marker of … The SA2-H group exhibited the greatest downregulation effect. …

The comparison of preliminary structure and intestinal anti-inflammatory and anti-oxidative activities of polysaccharides from different root parts of Angelica sinensis …

YF Zou, CY Li, YP Fu, QX Jiang, X Peng, LX Li… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance The root of Angelica sinensis, has been commonly used
in gynecology for centuries, and is normally applied divided into different parts in various …

The role of ferroptosis in diabetic

J Yang, Y Zhou - Diabetes and cardiovascular disease: new …, 2024 - books.google.com
… Astragaloside IV Active the NRF2 signalling pathway, upregulate the expression of GPX4, …
Resveratrol attenuate myocardial injury by inhibiting ferroptosis via inducing KAT5/GPX4 in …

Insight into the progress on natural dyes: sources, structural features, health effects, challenges, and potential

N Li, Q Wang, J Zhou, S Li, J Liu, H Chen - Molecules, 2022 - mdpi.com
… Alkannin and its enantiomer shikonin are valuable natural … In anti-diabetic activity, astaxanthin
could attenuate STZ-… in HT22 cells via the PI3K/Akt/Nrf2 signaling pathway and improved …