Long non-coding RNAs and JAK/STAT signaling pathway regulation in colorectal cancer development

A Ghasemian, HA Omear, Y Mansoori… - Frontiers in …, 2023 - frontiersin.org
Colorectal cancer (CRC) is one of the main fatal cancers. Cell signaling such as Janus
kinase/signal transducer … the lncRNA cross-talk in CRC through the JAK/STAT signaling pathway, …

[HTML][HTML] Cross-talk between antigen presenting cells and T cells impacts intestinal homeostasis, bacterial infections, and tumorigenesis

SJ Gaudino, P Kumar - Frontiers in immunology, 2019 - frontiersin.org
… a conserved tyrosine residue of signal transducers and activators of transcription (…
tumorigenesis compared to mice treated with unmodified IL-2 (158). The onset of colorectal cancer

Connexins and cAMP cross-talk in cancer progression and metastasis

CX Chen, KJ Luo, JP Yang, YC Huang, ER Cardenas… - Cancers, 2020 - mdpi.com
… Cx43 acts as a tumor suppressor in colorectal cancer, breast cancer, and glioma, whereas
… intracellular signal transduction [1,2]. Early studies indicated that cAMP signaling depends …

Cross-talk between YAP and RAR-RXR drives expression of stemness genes to promote 5-FU resistance and self-renewal in colorectal cancer cells

M Bauzone, M Souidi, AF Dessein, M Wisztorski… - Molecular cancer …, 2021 - AACR
signaling YAP/RAR-RXR cross-talk related to the activation status of the transcriptional
coactivator YAP in 5-FU–sensitive and –resistant colorectal cancer … YAP/RAR-RXR cross-talk and …

Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis

Y Yang, L Li, C Xu, Y Wang, Z Wang, M Chen, Z Jiang… - Gut, 2021 - gut.bmj.com
… and colorectal cancer, evolving transcriptional signature and immune response during human
… of CAC and its accumulation was dependent on CCL2 signal transduction. Blocking CCL2 …

The cross-talk between signaling pathways, noncoding RNAs and DNA damage response: emerging players in cancer progression

F Malakoti, F Alemi, S Younesi, M Majidinia, B Yousefi… - DNA repair, 2021 - Elsevier
… , have a significant function in the signal transduction step in the DDR pathway. A DNA …
cancer progression such as hepatocellular carcinoma, pancreatic and colorectal cancer through

Cross-talk between Wnt signaling and Src tyrosine kinase

JK Min, HS Park, YB Lee, JG Kim, JI Kim, JB Park - Biomedicines, 2022 - mdpi.com
… Aberrant Wnt signaling as well as increased Src activity is closely related to many diseases.
… Wnt signaling in cancer progress has most prominently been described for colorectal cancer

Cancer-associated neurogenesis and nerve-cancer cross-talk

DA Silverman, VK Martinez, PM Dougherty, JN Myers… - Cancer research, 2021 - AACR
… found in glioma tissue and facilitate gap-junction signal transmission (88, 90). In addition, …
Cholinergic stimulation also prevents colorectal cancer progression by inducing trefoil factor …

[HTML][HTML] CXCR4 and CXCR7 signaling pathways: a focus on the cross-talk between cancer cells and tumor microenvironment

S Santagata, C Ieranò, AM Trotta, A Capiluongo… - Frontiers in …, 2021 - frontiersin.org
… CXCL12 binding to CXCR4 triggers multiple signal transduction pathways that regulate …
EMT-signaling (36). CXCR7 mRNA and protein are overexpressed in colorectal cancer patients …

Anti-cancer therapeutic strategies based on HGF/MET, EpCAM, and tumor-stromal cross talk

K Barzaman, R Vafaei, M Samadi, MH Kazemi… - Cancer Cell …, 2022 - Springer
… , for example, non-small cell lung cancer (NSCLC) and colorectal cancer (CRC); also, it is …
as signal transducers contribute to Wnt downstream effectors to initiate and develop cancer. It …