… -sTn glycoform, which is associated with colonic inflammation and cancer. A computational
model demonstrated the signaling, cross-talk and dynamics involved in regulating gene …

… Colorectal cancer is one of the leading causes of death worldwide. Its incidence and …
increased during the past few years. Colorectal cancer cells cross-talk with other cells through …

… Signal transduction defines the precise series of molecular … as there is considerable
cross talk between such subcircuits. … Elevated EGFR signaling in colorectal cancer can be …

… the growth of cancer cells through apoptosis [37] and downregulation of signal transducer and
… its potential chemo-preventive properties in colorectal cancer and hepatic metastasis [39]. …

… JAKs catalyze phosphorylation of the signal transducer and activator of transcription 3 (…
cross-talk in cancer development, not only CRC. Better understanding of intercellular signaling …

… signal transduction. CAMs function as transmembrane proteins, the extracellular domain
stabilizes cells to bind to adjacent cells and ECM, while … the migration of colorectal cancer cells …

… modulate this pathway in prostate cancer. Finally, we … cancer as it is a challenging facet
of therapy development due to the complexity of signaling pathways interaction and cross-talk. …

… proliferation and motility of colorectal cancer cells, suggesting a … cancer cells to evade
apoptosis and promote cell growth via activating transcriptional factors, including signal transducer …

… cells (NF-κB) signaling and the activation of signal transducer and activator of transcription
(… can stimulate STAT-3 and STAT-6 signaling and leads to M2 macrophage polarization [53]. …

… for the canonical Wnt/β-catenin signal transduction. Herein, we show that activation of LRP5
… cross-talk between canonical Wnt/β-catenin signalling pathway, IL-6/STAT3 signalling …