… signaling pathways play important roles in renal fibrosis, and a recent study revealed an
interaction between HIF-1α and these two signal transduction pathways … promoting renal fibrosis …

… Renal hypoxia induced by CPB might be associated with abnormalities in both delivery and
… signaling pathways which are characteristic features of various fibrotic kidney diseases. …

… fibrosis in tissue samples from patients with chronic kidney disease. Our results suggest that
hypoxia induces renal fibrosis … -1α/HE4/NF-κB signaling pathway. Uncovering the molecular …

… Renal fibrosis is a common result of various … renal fibrosis is not merely a static and substantial
scar, but a dynamic and evolving process involving multiple complex signaling pathways …

… Renal interstitial fibrosis is a crucial metabolic change in the … of diabetic renal fibrosis and
discussed some signaling pathways … /STAT, and Notch pathways. The cross-talks among these …

… β and CTGF-mediated signaling pathways, causing extracellular matrix production and renal
fibrosis. renal tubulointerstitial fibrosis, hypoxia, cell cycle (G2/M) arrest, p53, HIF-1α, TGF-β …

… Mechanistically, HIF signaling may promote renal fibrosis via at least four mechanisms: (1) …
other pro-fibrotic signaling pathways such as TGF-β, NF-κB, Notch, and PI3K/Akt pathways; (3…

… During recent years, the studies on hypoxia inducible factor- (… are more likely to develop
into renal fibrosis eventually [3, 4]. … signaling pathways may be necessary to amplify fibrotic …

… Furthermore, the involvement of HIF-1α or HIF-2α signaling pathways on fiber … induced by
decreased oxygen availability and consequent hypoxic signaling in skeletal muscle fibrosis is …

… that hypoxia induces HK-2 cell apoptosis through a signaling pathway involving TGF-β1 via
Smad pathway induction of … cells leads to renal fibrosis and chronic kidney disease through …