… signaling pathways triggering renal fibrosis? (ii) What are new immunological mechanisms,
cells and molecules that contribute to renal fibrosis?, and finally (iii) How can renal fibrosis …

… Hypoxia induces endoplasmic reticulum (ER) stress sensors PKR-like ER kinase (PERK), …
transcription factor 6 (ATF6) to induce the UPR pathway. The PERK-mediated phosphorylation …

… In contrast, supraphysiologic HIF stabilization by von Hippel-Lindau deletion was reported
to induce renal fibrosis. The role of HIF stabilization in DKD progression may be context-…

… kidney disease, it has been found that EndMT is involved in the formation of renal fibrosis
and multiple signalling pathways such as TGF-β signalling pathway, Wnt signalling pathway …

… activating ERK1/2 and PI3K signaling pathways [27,28]. … Thus, tangeretin may encumber
renal fibrosis through inhibiting … To confirm that hypoxia induced podocyte foot process …

… After 4 weeks, the proteins in three branch signaling pathways of ER stress, including protein
kinase RNA (PKR)-like/Pancreatic ER kinase (PERK), activating transcription factor 6 (ATF-…

… to renal fibrosis. Our results stressed the importance of exosomal miRNA in renal fibrosis
and provide a theoretical basis for understanding the mechanism of acute kidney injury …

… signaling is the major pathway for renal fibrogenesis. Nevertheless, TGF-β1 can induce renal
fibrosis … non-canonical (SMAD-independent) signaling pathways, resulting in activation of …

… Given the increasing beneficial reports of H 2 , a growing number of H 2 signaling pathways
… Proposed signaling pathways involved in the protective effect of H 2 in CIH-induced renal …

… in lung, liver, and kidney fibrosis. Correcting these metabolic … Indeed, hypoxia induces the
proliferation and differentiation … of the PPAR and JAK-STAT signalling pathways. In green are …