… -9, a protein related to tumor cell metastasis; 3) Inhibition of … ) Activation of caspase-9 and
caspase-3, which provokes cell … simvastatin inhibits cancer cell growth by inducing apoptosis …

… Cell sensitivity to the two statins was found to be correlated (D) although significantly …
cancer cells was due to activation of apoptotic processes. We treated 3 TNBC and 1 non-TNBC …

… Simvastatin inhibited the activation of pyroptosis in GBM cells. U87 and … could regulate
pyroptosis of tumor cells. … also suppressed, results that were consistent with other related studies. …

… Statins can inhibit phosphorylation and activation of Akt and MAPK mitogenic signaling in …
In conclusion, in this study, it was demonstrated that simvastatin induced apoptosis by …

… Autophagy and apoptosis are interrelated via complex crosstalk … +SIM-induced apoptosis
and synergistic growth inhibition, … apoptosis induction and AMPK activation with downstream …

… The AKT kinase is activated by hormones, growth factors, … , we hypothesized that statin-induced
apoptosis in PC3 cells is … such as tumor necrosis factor-related apoptosis-inducing ligand …

… the effects of statins on proliferation and apoptosis in the ER-… cancer cell line MDA-MB-231
via activating ROS-induced … To further determine the correlation between miR-140-5p and …

… the correlation between statin use and lung cancer prognosis … higher simvastatin-induced
inhibition in lung cancer cells … and the Ras/Raf/mitogen-activated protein kinase kinase (MEK)/…

… Citation3 In addition, it induces apoptosis of cancer cells … Moreover, cancer cells may depend
on bcl-2, or related … of TAM and activates estrogen receptor α (ERα) and therefore induces …

… statin-induced apoptotic cell death in MCF-7 breast cancer cells, … Caspase activation
patterns confirmed our flow cytometry … cell lines, revealing prenylation of the cholesterol-related …