Single-cell transcriptomics reveals spatial and temporal turnover of keratinocyte differentiation regulators
… that specify epidermis structure and function. This article utilizes single-cell RNA-seq data
… transcriptional regulation of skin development and homeostasis genes, organizing them by …
… transcriptional regulation of skin development and homeostasis genes, organizing them by …
Single cell transcriptomics of human epidermis identifies basal stem cell transition states
S Wang, ML Drummond, CF Guerrero-Juarez… - Nature …, 2020 - nature.com
… single cell-RNA sequencing to interrogate basal stem cell heterogeneity of human interfollicular
epidermis and find four spatially … specific gene expression signatures that are strongly …
epidermis and find four spatially … specific gene expression signatures that are strongly …
[HTML][HTML] Single-cell transcriptome profiling reveals dermal and epithelial cell fate decisions during embryonic hair follicle development
W Ge, SJ Tan, SH Wang, L Li, XF Sun, W Shen… - Theranostics, 2020 - ncbi.nlm.nih.gov
… , we for the first time revealed the dermal and epidermal cell lineage … signatures of embryonic
hair follicle progenitors using unbiased scRNA-seq. Based on single-cell transcriptome …
hair follicle progenitors using unbiased scRNA-seq. Based on single-cell transcriptome …
[PDF][PDF] Defining epidermal basal cell states during skin homeostasis and wound healing using single-cell transcriptomics
… Using single-cell RNA sequencing coupled with RNAScope … skin that differ in metabolic
preference and become spatially … response) and EMT signatures in WO basal cells (Figure 3C). …
preference and become spatially … response) and EMT signatures in WO basal cells (Figure 3C). …
Integrating Single‐Cell and Spatial Transcriptomics Reveals Heterogeneity of Early Pig Skin Development and a Subpopulation with Hair Placode Formation
Y Wang, Y Jiang, G Ni, S Li, B Balderson… - Advanced …, 2024 - Wiley Online Library
… In this study, we generated single-cell and spatial transcriptomes of fetal pig skin during …
and spatial positions, we created an integrated transcriptome atlas of the entire embryonic skin …
and spatial positions, we created an integrated transcriptome atlas of the entire embryonic skin …
Single-Cell and Spatial Transcriptomic Analysis of Human Skin Delineates Intercellular Communication and Pathogenic Cells
… 0.82 for granular cells), further supporting their early differentiating status (Supplementary
Figure S5f). Examination of the spinous II signature in pseudotime revealed that signature …
Figure S5f). Examination of the spinous II signature in pseudotime revealed that signature …
Single cell transcriptomics of human epidermis reveals basal stem cell transition states
S Wang, ML Drummond, CF Guerrero-Juarez… - bioRxiv, 2019 - biorxiv.org
… single cell-RNA sequencing to interrogate basal stem cell heterogeneity of human interfollicular
epidermis and find at least four spatially … specific gene expression signatures that are …
epidermis and find at least four spatially … specific gene expression signatures that are …
[HTML][HTML] Single-cell transcriptomics reveals the molecular anatomy of sheep hair follicle heterogeneity and wool curvature
S Wang, T Wu, J Sun, Y Li, Z Yuan… - Frontiers in Cell and …, 2021 - frontiersin.org
… and revealed the differentiation and spatial signatures underlying … We detected 19,097
genes in skin cells for the straight wool … After QC, we obtained 15,830 single-cell transcriptome …
genes in skin cells for the straight wool … After QC, we obtained 15,830 single-cell transcriptome …
[PDF][PDF] Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation
T Krausgruber, A Redl, D Barreca, K Doberer… - Immunity, 2023 - cell.com
… and non-lesional skin by using gene signatures derived from our … skin granulomas, we
performed dimensionality reduction and unsupervised clustering of the single-cell transcriptome …
performed dimensionality reduction and unsupervised clustering of the single-cell transcriptome …
Single‐cell transcriptomic analysis of small and large wounds reveals the distinct spatial organization of regenerative fibroblasts
… type shares a similar gene signature to the murine … skin regeneration. The WIHN model
system has been utilized in studies to reveal the importance of epidermal stem cell differentiation …
system has been utilized in studies to reveal the importance of epidermal stem cell differentiation …