Role of SIRT1 in isoflurane conditioning-induced neurovascular protection against delayed cerebral ischemia secondary to subarachnoid hemorrhage

M Liu, K Jayaraman, T Giri, GJ Zipfel… - International journal of …, 2021 - mdpi.com
… thrombosis), leading to improved neurological deficits; (2) … microvessel thrombosis after SAH
is not mediated through SIRT1. … Isoflurane-induced changes in the SIRT1 mRNA expression …

AMPK-SIRT1-PGC1α signal pathway influences the cognitive function of aged rats in sevoflurane-induced anesthesia

XY Yang, QJ Li, WC Zhang, SQ Zheng, ZJ Qu… - Journal of Molecular …, 2020 - Springer
… mass and MMP levels, and AMPK, SIRT1 and PGC-1α protein expressions. … improved
after the administration of AICAR, and EX527 could reverse AICAR-induced improvements

[HTML][HTML] Surgery-induced downregulation of hippocampal sirtuin-1 contributes to cognitive dysfunction by inhibiting autophagy and activating apoptosis in aged mice

QJ Fang, BH Chi, QC Lin, CM Huang… - American Journal of …, 2020 - ncbi.nlm.nih.gov
… of Sirtuin-1 (SIRT1)-mediated autophagy and apoptosis in … isoflurane induced neuroapoptosis
and resulted in cognitive … associated memory deterioration following hyperbaric oxygen

SIRT1 mediates improvement of cardiac surgery-induced postoperative cognitive dysfunction via the TLR4/NF-κB pathway

J Shi, X Zou, K Jiang, F Wang - The World Journal of Biological …, 2020 - Taylor & Francis
… : for instance, learning and memory impairment, difficulty with … neuroprotective effects of
hyperbaric oxygen preconditioning (… Similarly, in isoflurane-induced cognitive deficits of middle-…

Hyperbaric oxygen treatment—from mechanisms to cognitive improvement

I Gottfried, N Schottlender, U Ashery - Biomolecules, 2021 - mdpi.com
… with memory loss at baseline to HBOT showed improved … This was mediated by an increase
in SIRT1, a class III histone … [84], and SIRT1 was also shown to play a role in recovery after

Research progress of postoperative cognitive dysfunction in cardiac surgery under cardiopulmonary bypass

YM Zhuang, JY Xu, K Zheng, H Zhang - Ibrain, 2023 - Wiley Online Library
… The pathophysiological changes of memory impairment include abnormal … SIRT1
mediates improvement of isofluraneinduced memory impairment following hyperbaric oxygen

SIRT1 Mediates H2S-Ameliorated Diabetes-Associated Cognitive Dysfunction in Rats: Possible Involvement of Inhibiting Hippocampal Endoplasmic Reticulum Stress …

J He, Z Chen, X Kang, L Wu, JM Jiang, SM Liu… - Neurochemical …, 2021 - Springer
… conducted following hippocampus tissue abtained after behavioral … recognition and memory
disability in STZ-diabetic rats. … SIRT1 has been demonstrated to mediate hyperbaric oxygen

Role of SIRT1 in sepsis‐induced encephalopathy: Molecular targets for future therapies

AH Shehata, AF Anter… - European Journal of …, 2023 - Wiley Online Library
impairments induced by sepsis may persist longer even after … downstream signalling cascades
mediated by SIRT1 and its … LPS produced marked memory impairments and depression. …

κ‑opioid receptor agonist U50488H attenuates postoperative cognitive dysfunction of cardiopulmonary bypass rats through the PI3K/AKT/Nrf2/HO‑1 pathway

J Fan, L Li, P Qu, Y Diao, Y Sun - Molecular Medicine …, 2021 - spandidos-publications.com
… In recent years, the protective effects mediated by … stress following CPB and improve cognitive
functions following CPB are … and can reverse the memory impairment caused by CPB (44). …

Survey of molecular mechanisms of hyperbaric oxygen in tissue repair

J Lindenmann, C Smolle, LP Kamolz… - International Journal of …, 2021 - mdpi.com
… proliferation and the improvement of wound healing [18]. HBO-induced enhancement of …
was further found to trigger thioredoxin-mediated signaling cascades [21,22,23], which is a …