Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer's dementia

K Kaneshwaran, M Olah, S Tasaki, L Yu… - Science …, 2019 - science.org
… We assessed sleep fragmentation by actigraphy and related this to cognitive function, to …
Greater sleep fragmentation was associated with higher neocortical expression of genes …

[HTML][HTML] Brain and cognitive correlates of sleep fragmentation in elderly subjects with and without cognitive deficits

C André, C Tomadesso, R de Flores, P Branger… - Alzheimer's & Dementia …, 2019 - Elsevier
… factor for Alzheimer's disease. However, no study has assessed the relationships … in sleep
quality have been related to cognitive decline and increased risk of developing dementia [2], [3…

Sleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis

W Xu, CC Tan, JJ Zou, XP Cao, L Tan - Journal of Neurology …, 2020 - jnnp.bmj.com
… domains (such as daytime dysfunction, fragmentation, latency and subjective quality). As for
the subtypes of … . Self-Reported sleep disturbance is associated with Alzheimer's disease

Sleep profile predicts the cognitive decline of mild-moderate Alzheimer's disease patients

ADS Targa, ID Benítez, F Dakterzada, A Carnes… - Sleep, 2021 - academic.oup.com
… to their sleep (one with a propensity to deepen the sleep and … the lighter sleep stage), we
hypothesized that the cognitive decline … In fact, sleep disturbances such as sleep fragmentation, …

Self‐reported sleep fragmentation and sleep duration and their association with cognitive function in PROTECT, a large digital community‐based cohort of people …

JA Aakre, J Schulz, C Ballard, A Corbett… - … Journal of Geriatric …, 2023 - Wiley Online Library
… found no link between insomnia and dementia or Alzheimer's disease. Surprisingly, in the
latter, fragmented sleep was associated with lower dementia risk and better cognition scores. …

Is disrupted sleep a risk factor for Alzheimer's disease? Evidence from a two-sample Mendelian randomization analysis

EL Anderson, RC Richmond, SE Jones… - International journal …, 2021 - academic.oup.com
… (eg cognitive function at a single time point, 14 cognitive decline … ), nocturnal sleep duration
and sleep fragmentation. Note … associations of sleep traits on risk of Alzheimer's disease (AD…

Implications of sleep disturbance and inflammation for Alzheimer's disease dementia

MR Irwin, MV Vitiello - The Lancet Neurology, 2019 - thelancet.com
… that sleep disturbance contributes to cognitive decline and might also increase the risk of
Alzheimer's disease dementia by … That sleep disturbance would be a candidate risk factor for …

[HTML][HTML] Sleep disorders in Alzheimer's disease: the predictive roles and potential mechanisms

H Kuang, YG Zhu, ZF Zhou, MW Yang… - Neural Regeneration …, 2021 - journals.lww.com
Alzheimer’s disease-specific sleep changes, including abnormal non-rapid eye movement
sleep, sleep fragmentation, and sleep-… with cognitive decline, sleep fragmentation did not …

Sleep fragmentation and cognitive trajectories after critical illness

ME Wilcox, MP McAndrews, J Van, JC Jackson, R Pinto… - Chest, 2021 - Elsevier
… Given the association of sleep disturbance with cognitive impairment in a variety of
patient populations, 18 , 20 , 39 we set out to determine whether early actigraphy estimated …

[HTML][HTML] Sleep disturbance as a potential modifiable risk factor for Alzheimer's disease

EN Minakawa, K Wada, Y Nagai - International journal of molecular …, 2019 - mdpi.com
… have suggested that sleep disturbance could be a risk factor for cognitive decline and AD. …
that demonstrated an association between sleep fragmentation and an increased risk of AD […