Nanoformulations of small molecule protein tyrosine kinases inhibitors potentiate targeted cancer therapy
… Therefore, PTKs have become the most promising targets for … -of-art of small molecule protein
tyrosine kinase inhibitors and the … for future research of small molecule TKIs are addressed. …
tyrosine kinase inhibitors and the … for future research of small molecule TKIs are addressed. …
Recent advances in targeted small‐molecule inhibitor therapy for non–small‐cell lung cancer—an update
… Kinase (ALK) inhibitors have been promising tools for … mutations and neurotrophic receptor
tyrosine kinase (NTRK) … of targeted small-molecule EGFR Inhibitors and ALK inhibitors in …
tyrosine kinase (NTRK) … of targeted small-molecule EGFR Inhibitors and ALK inhibitors in …
A recent update on small‐molecule kinase inhibitors for targeted cancer therapy and their therapeutic insights from mass spectrometry‐based proteomic analysis
… target the extracellular domain of a receptor tyrosine kinase. … cell malignancies and represents
a promising target to inhibit tumour … with computational tools for mapping kinase–substrate …
a promising target to inhibit tumour … with computational tools for mapping kinase–substrate …
Recent advances in the discovery of multitargeted tyrosine kinase inhibitors as anticancer agents
T Guo, S Ma - ChemMedChem, 2021 - Wiley Online Library
… Tyrosine kinase inhibitors include single-targeted and MT-… more than 60 small-molecule
protein kinase inhibitors and most … into receptor tyrosine kinase (RTK) and non-receptor tyrosine …
protein kinase inhibitors and most … into receptor tyrosine kinase (RTK) and non-receptor tyrosine …
Small-molecule kinase inhibitors for the treatment of nononcologic diseases
Z Xie, X Yang, Y Duan, J Han… - Journal of medicinal …, 2021 - ACS Publications
… has revealed that kinases are promising drug targets for different … As a type III receptor tyrosine
kinase, FMS-like tyrosine kinase … that these ASK1 inhibitors might be useful tools to further …
kinase, FMS-like tyrosine kinase … that these ASK1 inhibitors might be useful tools to further …
Small molecule approaches to treat autoimmune and inflammatory diseases (Part I): Kinase inhibitors
J Zheng, J Wu, X Ding, HC Shen, G Zou - Bioorganic & Medicinal Chemistry …, 2021 - Elsevier
… Targeting spleen tyrosine kinase Spleen tyrosine kinase (SYK), a non-receptor tyrosine kinase
… RIP2 activity shows promise as a therapeutic approach for the treatment of autoimmune …
… RIP2 activity shows promise as a therapeutic approach for the treatment of autoimmune …
Targeting tyrosine kinases in ovarian cancer: small molecule inhibitor and monoclonal antibody, where are we now?
A Rendell, I Thomas-Bland, L McCuish, C Taylor… - Biomedicines, 2022 - mdpi.com
… targeting of receptor tyrosine kinases in ovarian cancer. Broadly, drug classes that inhibit
tyrosine kinase/… Another RTK target with promising preclinical results and potential influence …
tyrosine kinase/… Another RTK target with promising preclinical results and potential influence …
Small molecule inhibitors targeting the cancers
… binding to and activating the receptor tyrosine kinase (RTK) c-KIT, also known as stem cell
growth factor … Selective FGFR inhibitors are a promising method to treat FGFR- altered tumors. …
growth factor … Selective FGFR inhibitors are a promising method to treat FGFR- altered tumors. …
Progress in the development of small molecular inhibitors of the Bruton's tyrosine kinase (BTK) as a promising cancer therapy
XJ Liu, XJ Pang, XY Yuan, GX Yu, YR Li… - Bioorganic & medicinal …, 2021 - Elsevier
… BTK, a non-receptor cytoplasmic protein tyrosine kinase, belongs to the Tec family of non-…
a promising drug target for the treatment of B cell malignant tumors. Small molecule inhibitors …
a promising drug target for the treatment of B cell malignant tumors. Small molecule inhibitors …
AXL receptor tyrosine kinase as a promising anti-cancer approach: functions, molecular mechanisms and clinical applications
C Zhu, Y Wei, X Wei - Molecular cancer, 2019 - Springer
… strategies for targeting AXL in the treatment of cancer.AXL-targeted drugs, either as single
agents or in combination with conventional chemotherapy or other small molecule inhibitors, …
agents or in combination with conventional chemotherapy or other small molecule inhibitors, …