… Therefore, PTKs have become the most promising targets for … -of-art of small molecule protein
tyrosine kinase inhibitors and the … for future research of small molecule TKIs are addressed. …

… Kinase (ALK) inhibitors have been promising tools for … mutations and neurotrophic receptor
tyrosine kinase (NTRK) … of targeted small-molecule EGFR Inhibitors and ALK inhibitors in …

… target the extracellular domain of a receptor tyrosine kinase. … cell malignancies and represents
a promising target to inhibit tumour … with computational tools for mapping kinase–substrate …

… Tyrosine kinase inhibitors include single-targeted and MT-… more than 60 small-molecule
protein kinase inhibitors and most … into receptor tyrosine kinase (RTK) and non-receptor tyrosine …

… has revealed that kinases are promising drug targets for different … As a type III receptor tyrosine
kinase, FMS-like tyrosine kinase … that these ASK1 inhibitors might be useful tools to further …

… Targeting spleen tyrosine kinase Spleen tyrosine kinase (SYK), a non-receptor tyrosine kinase
… RIP2 activity shows promise as a therapeutic approach for the treatment of autoimmune …

… targeting of receptor tyrosine kinases in ovarian cancer. Broadly, drug classes that inhibit
tyrosine kinase/… Another RTK target with promising preclinical results and potential influence …

… binding to and activating the receptor tyrosine kinase (RTK) c-KIT, also known as stem cell
growth factor … Selective FGFR inhibitors are a promising method to treat FGFR- altered tumors. …

… BTK, a non-receptor cytoplasmic protein tyrosine kinase, belongs to the Tec family of non-…
a promising drug target for the treatment of B cell malignant tumors. Small molecule inhibitors …

… strategies for targeting AXL in the treatment of cancer.AXL-targeted drugs, either as single
agents or in combination with conventional chemotherapy or other small molecule inhibitors, …