Intestinal helminth infection impairs oral and parenteral vaccine efficacy

Y Zhang, LKC Hardy, CM Kapita, JA Hall… - The Journal of …, 2023 - journals.aai.org
suppressed Th1-skewed OVA-specific Ab responses to our live … and elimination of soil-transmitted
helminth infection beyond … of infection and disease burden of soil transmitted helminth

Comparative analysis of poliovirus-specific IgA and cytokine levels in the sera of Ascaris lumbricoides-infected and helminth-negative Nigerian children after oral …

KS Akinwande, GO Arinola - African Journal of Clinical and Experimental …, 2021 - ajol.info
helminth infection is associated with altered immune responses and compromised vaccine
efficacy in infected … of intestinal parasitic worms known as soil-transmitted helminths (STH) (1)…

[HTML][HTML] Immunological Considerations for Schistosoma Vaccine Development: Transitioning to Endemic Settings

E Driciru, JPR Koopman, S Cose, AA Siddiqui… - Frontiers in …, 2021 - frontiersin.org
… and soil-transmitted helminths) and viral (Cytomegalovirus) … 107), indicating a suppressed
immune response. Particularly, … hand, STH infections do not alter IgG antibody responses to …

[HTML][HTML] Oral peptide vaccine against hookworm infection: correlation of antibody titers with protective efficacy

AO Shalash, L Becker, J Yang, P Giacomin, M Pearson… - Vaccines, 2021 - mdpi.com
… mucosal antibody responses and worm burden reduction was, in general, not statistically …
compromising safety via allergic or autoimmune responses. The lack of anti-cathepsin-D …

Under the Influence: The Systemic Consequences of Helminth Infection

RM Maizels - Helminth Infections and their Impact on Global Public …, 2022 - Springer
… volvulus infection has been reported to compromise the … memory-like antibody responses
in neonates from infected mothers (… Soil-transmitted helminths are not known to be neurotropic …

Regulation of immunity and allergy by helminth parasites

RM Maizels - Allergy, 2020 - Wiley Online Library
… of the parasite 15; in others, regulation is not so well-ordered and inflammatory responses to
the parasite … , in respect of compromised responses to vaccination 18 and certain microbial …

[HTML][HTML] Host immunity and inflammation to pulmonary helminth infections

JE Weatherhead, P Gazzinelli-Guimaraes… - Frontiers in …, 2020 - frontiersin.org
… leading to severe, pulmonary compromise while others … include the major soil-transmitted
helminths, Ascaris lumbricoides and … anti-enzyme antibody responses to parasite gut digestive …

[HTML][HTML] Parasitic helminth infections in humans modulate Trefoil Factor levels in a manner dependent on the species of parasite and age of the host

B Adewale, JR Heintz, CF Pastore… - PLoS Neglected …, 2021 - journals.plos.org
… TFF2 could contribute to suppressed inflammatory responses in the context of hookworm …
Soil-transmitted helminth reinfection four and six months after mass drug administration: results …

Helminth infections and immunosenescence: The friend of my enemy

A Abdoli, HM Ardakani - Experimental gerontology, 2020 - Elsevier
… of helminth infections, especially soil-transmitted helminths … TH1 and TH17 cells compromises
during helminth infections. … had a delayed helminth-specific IgG1 antibody response, lower …

[HTML][HTML] Immunomodulation resulting of helminth infection could be an opportunity for immunization against tuberculosis and mucosal pathogens

KL Chin, L Fonte, BH Lim, ME Sarmiento… - Frontiers in …, 2023 - frontiersin.org
Infections caused by soil-transmitted helminths (STH) and … weakened with increasing age
(49). Considering the negative influence of the Th2 response associated to helminth infections