Mps1 releases Mad1 from nuclear pores to ensure a robust mitotic checkpoint and accurate chromosome segregation

M Osswald, S Cunha-Silva, J Goemann, J Barbosa… - bioRxiv, 2019 - biorxiv.org
… of EGFP-Megator 1178-1655 with high spatiotemporal resolution … Amino acids in dark gray
background are conserved and … imaging the mitotic progression of Megator phosphomutants …

Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation

S Cunha-Silva, M Osswald, J Goemann… - Journal of Cell …, 2020 - rupress.org
… underpinnings controlling the spatiotemporal redistribution of … threonine in vertebrate
orthologues and T1390 is well conserved … of Megator phosphomutants to arrest in mitosis when …

The nuclear envelope in higher plant mitosis and meiosis

M Pradillo, D Evans, K Graumann - Nucleus, 2019 - Taylor & Francis
cell division in which the nuclear envelope (NE) breaks down to allow the mitotic spindle
to … is widely conserved [Citation92]. However, the possible involvement of other NE-associated …

The nuclear envelope in higher plant mitosis and meiosis

M Pradillo Orellana, D Evans, K Graumann - 2019 - docta.ucm.es
… breaks down to allow the mitotic spindle to connect with the chro… Envelope Associated Protein
(NEAP) family is conserved in … of Tpr/ Mlp1/Mlp2/megator, is involved in mRNA export and …

Spatiotemporal coordination of Greatwall-Endos-PP2A promotes mitotic progression

M Larouche, D Kachaner, P Wang, K Normandin… - Journal of Cell …, 2021 - rupress.org
… for mitotic regulation. We find that Tws shuttles through the nucleus via a conserved nuclear
… GFP-Tws resembles the spindle matrix, a gel-like structure derived from an array of nuclear …

The microtubule- and PP1-binding activities of Drosophila melanogaster Spc105 control the kinetics of SAC satisfaction

MR Audett, EL Johnson, JM McGory… - Molecular Biology of …, 2022 - Am Soc Cell Biol
… inducing protein oligomerization with high spatiotemporal control … pattern was observed in
mitotic cells expressing mCherry-… (here controlled by ABK) is evolutionarily conserved in flies. …

Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint

M Jackman, C Marcozzi, M Barbiero, M Pardo… - Journal of Cell …, 2020 - rupress.org
conserved in eukaryotes, but how these multiple protein … Cyclin B1-Cdk is the primary
kinase that drives mitotic … an acidic face of the kinetochore checkpoint protein, MAD1, where it …

Disrupted nuclear import of cell cycle proteins in Huntington's/PolyQ disease causes neurodevelopment defects in cellular and Drosophila model

SK Dubey, TE Lloyd, MG Tapadia - Heliyon, 2024 - cell.com
… that occur in a spatiotemporal manner during development … Htt128 reduces cell division as
compared to the control (ELAV-… antibody, which binds to the conserved FG-repeat containing …

Correct dosage of X chromosome transcription is controlled by a nuclear pore component

JR Aleman, TM Kuhn, P Pascual-Garcia, J Gospocic… - Cell reports, 2021 - cell.com
… that localizes to the putative spindle matrix during mitosis in Drosophila. … Nuclear pore
proteins nup153 and megator define transcriptionally active regions in the Drosophila genome. …

[PDF][PDF] Characterizing the effects of jasplakinolide on Mesostoma ehrenbergii primary spermatocytes to study the role of actin during chromosome movement

DS Patel - 2021 - yorkspace.library.yorku.ca
… Now that I have described normal cell division and the different … spindle matrix function,
we know it consists of a variety of nuclear-derived proteins (eg, Skeletor, Chromator, Megator