A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling
JN Van Der Veen, S Lingrell, N McCloskey… - The FASEB …, 2019 - Wiley Online Library
… the role of hepatic phospholipid synthesis and metabolism in … , we analyzed DAG levels in
microsomal fractions of the liver. … A specific biochemical and cytological marker for a unique …
microsomal fractions of the liver. … A specific biochemical and cytological marker for a unique …
Hepatic lipid profile in mice fed a choline-deficient, low-methionine diet resembles human non-alcoholic fatty liver disease
EM Haberl, R Pohl, L Rein-Fischboeck… - Lipids in Health and …, 2020 - Springer
… Phosphatidylcholine and lysophosphatidylcholine … The tumor specific lipid profile,
however, did not resemble the … at a comprehensive analysis of the liver lipidome of mice fed a …
however, did not resemble the … at a comprehensive analysis of the liver lipidome of mice fed a …
Phospholipid synthesis in mammalian cells
ND Ridgway - Biochemistry of lipids, lipoproteins and membranes, 2021 - Elsevier
… with specific cellular functions that are revealed through analysis … is a substrate for the
synthesis of phosphatidylcholine (PC), … Liver-specific knockout of Pcyt1a in mice did not affect …
synthesis of phosphatidylcholine (PC), … Liver-specific knockout of Pcyt1a in mice did not affect …
Phosphatidylcholine (18: 0/20: 4), a potential biomarker to predict ethionamide‐induced hepatic steatosis in rats
K Muta, K Saito, Y Kemmochi… - Journal of Applied …, 2022 - Wiley Online Library
… (Gnpat) gene synthesizing ePCs in peroxisomes. This result … analysis for the plasma and
liver lipids in an ETH-induced … , air-conditioned room maintained under specific pathogen-free …
liver lipids in an ETH-induced … , air-conditioned room maintained under specific pathogen-free …
[PDF][PDF] Impaired Hepatic Phosphatidylcholine Synthesis Leads to Cholestasis in Mice Challenged With a High‐Fat Diet
S Wan, F Kuipers, R Havinga, H Ando… - Hepatology …, 2019 - Wiley Online Library
… Plasma and hepatic indices of liver function and parameters … , stored overnight at 4C, and
analyzed the following morning. … acyl chain specificity of biliary phosphatidylcholines in mice is …
analyzed the following morning. … acyl chain specificity of biliary phosphatidylcholines in mice is …
… tracer phospholipidomics reveals contributions of key phospholipid biosynthetic pathways to low hepatocyte phosphatidylcholine to phosphatidylethanolamine ratio …
… trigger for the altered hepatic phosphatidylcholine to … , we exploited flux analysis, a highly
specific and sensitive … pathway and compare the newly synthesized phospholipid pool to the …
specific and sensitive … pathway and compare the newly synthesized phospholipid pool to the …
[HTML][HTML] A human liver chimeric mouse model for non-alcoholic fatty liver disease
B Bissig-Choisat, M Alves-Bezerra, B Zorman… - JHEP Reports, 2021 - Elsevier
… TIRF mice develop human hepatocyte-specific steatosis after … 3-one (an intermediate in
the synthesis of bile acids) and the … tested in the present work, human liver chimeric mice …
the synthesis of bile acids) and the … tested in the present work, human liver chimeric mice …
Analysis of serum lysophosphatidylethanolamine levels in patients with non-alcoholic fatty liver disease by liquid chromatography-tandem mass spectrometry
Y Yamamoto, T Sakurai, Z Chen, T Furukawa… - Analytical and …, 2021 - Springer
… synthesized LysoPEs of sn-1 type and performed analysis of … enzyme to metabolize LysoPC
to phosphatidylcholine, were … ) were identified as specific lysophospholipid acyltransferase …
to phosphatidylcholine, were … ) were identified as specific lysophospholipid acyltransferase …
Choline kinetics in neonatal liver, brain and lung—lessons from a rodent model for neonatal care
W Bernhard, M Raith, A Shunova, S Lorenz… - Nutrients, 2022 - mdpi.com
… growth because the synthesis of phosphatidylcholine (PC), … of choline deficiency, we
analyzed choline and choline … kept under standardized, specific pathogen-free conditions on …
analyzed choline and choline … kept under standardized, specific pathogen-free conditions on …
LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover
Y Tanaka, Y Shimanaka, A Caddeo, T Kubo, Y Mao… - Gut, 2021 - gut.bmj.com
… the hepatocyte-specific Lpiat1 knockout mice to investigate … species of phosphatidylcholine
(PC) in Lpiat1 Δ/Δ liver were … in liver fat content, we then examined the rate of hepatic TG …
(PC) in Lpiat1 Δ/Δ liver were … in liver fat content, we then examined the rate of hepatic TG …