[HTML][HTML] Label-free macroscopic fluorescence lifetime imaging of brain tumors

M Lukina, K Yashin, EE Kiseleva, A Alekseeva… - Frontiers in …, 2021 - frontiersin.org
lifetime in the spectral band of NAD(P)H. In this study, the FLIM images were recorded from
freshly excised whole rat brains … ones we measured the mean fluorescence lifetimes around …

[HTML][HTML] Flavin fluorescence lifetime and autofluorescence optical redox ratio for improved visualization and classification of brain tumors

D Reichert, LI Wadiura, MT Erkkilae… - Frontiers in …, 2023 - frontiersin.org
… capability to measure the fluorescence lifetime of fluorophores, … fluorescence lifetime
with fluorescence spectra acquired ex-… Frequency-domain fluorescence lifetime imaging (FD-FLIM) …

Interrogation of glioma metabolism on macroscale by FLIM

MV Shirmanova, M Lukina, EB Kisileva… - … Microscopy in the …, 2019 - spiedigitallibrary.org
… the rat models indicate that the metabolism in brain tumors … Usually, further the signal can
be separated into two spectral or … P)H fluorescence lifetime was measured in the area of tumor, …

[HTML][HTML] Optical signatures derived from deep UV to NIR excitation discriminates healthy samples from low and high grades glioma

H Mehidine, A Chalumeau, F Poulon, F Jamme… - Scientific Reports, 2019 - nature.com
… primary from secondary brain tumors using deep UV and NIR … spectral range, we used
spectral and lifetime measurements … Unlike with our previous results on rats 26 and fixed tissues …

Optical properties of human brain and tumour tissue: an ex vivo study spanning the visible range to beyond the second near‐infrared window

J Shapey, Y Xie, E Nabavi, M Ebner… - Journal of …, 2022 - Wiley Online Library
… The mean value of measured total reflectance spectra R (R T … reflectance measurements[25,
36] and frequency-domain … We observed that the spectral curves of every brain tumour

In vivo real-time discrimination among glioma, infiltration zone, and normal brain tissue via autofluorescence technology

KT Chang, YY Lin, YY Lin, YL Lin, H Cheng, Y Chang… - World Neurosurgery, 2019 - Elsevier
… The fluorescence spectra of the lysates were measured using … compared with those of the
brain tumor histology identified by … profile of the rat brain ipsilateral to the tumor shows changes …

Photodynamic therapy of brain tumors and novel optical coherence tomography strategies for in vivo monitoring of cerebral fluid dynamics

A Abdurashitov, V Tuchin… - Journal of Innovative …, 2020 - World Scientific
… –180 nm) in the brain of rats. Trinidad in experiments in vitro … where l c is the length of
coherence volume is axial direction, … in spectral domain to perform detection of spectral properties …

Quantitative subsurface spatial frequency‐domain fluorescence imaging for enhanced glioma resection

M Sibai, DJ Wirth, F Leblond, DW Roberts… - Journal of …, 2019 - Wiley Online Library
… of [PpIX] in an intracranial rat tumor model with 90% accuracy … Here, we measure the
fluorescence modulation amplitude as … Hence, spectral subtraction will be required, and it will also …

Combined autofluorescence and diffuse reflectance for brain tumour surgical guidance: initial ex vivo study results

H Lu, K Grygoryev, N Bermingham… - Biomedical Optics …, 2021 - opg.optica.org
… The optical measurements in this study were processed … of 100% for in vivo skin tumour
with topically applied 5-ALA. … size allowed, this procedure was repeated, and spectra were …

Nanosecond compressive fluorescence lifetime microscopy imaging via the RATS method with a direct reconstruction of lifetime maps

J Junek, K Žídek - Optics Express, 2023 - opg.optica.org
… digital laser modulation in RATS, it is possible to implement the measurement of PL dynamics
with … Since the entire spectrum of lifetimes is obtained from the zeroth step, it subsequently …