Oscillometry of the respiratory system: a translational opportunity not to be missed

LKA Lundblad, A Robichaud - American Journal of …, 2021 - journals.physiology.org
… research over the other techniques where the two sites differ (eg, … as being hyperresponsive
to various inhaled stimuli, a … of a bronchodilator response in diagnosing asthma and that its …

Back to the future: re-establishing guinea pig in vivo asthma models

M Adner, BJ Canning, H Meurs, W Ford… - Clinical …, 2020 - portlandpress.com
between inhaled matter, local host defense in the airways, and systemic immunological and
endocrine responses lead to different … perfect correlation between antagonist potencies at …

Fusion Proteins as Selective Inducers of Constitutive Activity and Tools to Discriminate the Biased Signaling Profile of β2 Adrenoceptor Ligands

EY Lucero Garcia Rojas - 2021 - uh-ir.tdl.org
… This is the case of salbutamol, a selective β2AR agonist for asthma … to antagonists since
these ligands don’t show any functional … -response curves depend on the bioassay employed to …

[图书][B] Medical pharmacology at a glance

MJ Neal - 2020 - books.google.com
… and the concentration of the agonist can be measured by using bioassays. The first part of
Other routes These include inhalation (eg volatile anaesthetics, some drugs used in asthma) …

[图书][B] Rang & Dale's Pharmacology: Rang & Dale's Pharmacology E-Book

JM Ritter, RJ Flower, G Henderson, YK Loke… - 2023 - books.google.com
asthma 391 Drugs used to treat and prevent asthma 393 … IIb/ IIIa antagonist to prevent
reocclusion. Glycoprotein IIb/IIIa … -acting bronchodilator, eg salbutamol, given by inhalation on …

Bioequivalence of Orally Inhaled Drug Products: Challenges and Opportunities

JE Hastedt, EB Getz - … Inhalation Aerosol Technology, Third …, 2019 - taylorfrancis.com
… powder inhaler (DPI) emptying rate (which affects the flow … of inhaled fluticasone propionate
in asthmatic patients are … bioassay allows detection even of differences between manu…

[PDF][PDF] PrTEVA-MONTELUKAST

T Standard - 2020 - pdf.hres.ca
Based on biochemical and pharmacological bioassays, it … to asthmatics who require higher
doses of inhaled … TEVA-MONTELUKAST is a leukotriene receptor antagonist that blocks …

[图书][B] Dale's Pharmacology Condensed: Dale's Pharmacology Condensed E-Book

CP Page, S Pitchford - 2019 - books.google.com
… of physiological antagonism is salbutamol (albuterol in the United States; used to treat the
acute asthmaticInhalation is used for anaesthetic gases (Ch. 27) and in treatment of bronchial …

[HTML][HTML] Use of precision cut lung slices as a translational model for the study of lung biology

G Liu, C Betts, DM Cunoosamy, PM Åberg… - Respiratory …, 2019 - Springer
… contraction in response to specific agonists and antagonists. … In the context of asthma,
inhaled corticosteroids control asthma … as a bioassay for live tissue banking. A viability study of …

[PDF][PDF] Characterising pulmonary artery changes in mouse models of lung disease

E Lamanna - 2020 - scholar.archive.org
different techniques were validated to maximise their use for future experiments. Contractile
responses … ex vivo using PCLS as it is not possible to mimic the route of inhaled or systemic …