Genome‐wide analysis of acute traumatic spinal cord injury‐related RNA expression profiles and uncovering of a regulatory axis in spinal fibrotic scars
W Wang, J Li, Z Zhang, H Ma, Q Li, H Yang… - Cell …, 2021 - Wiley Online Library
… critical for posttranscriptional and transcriptional regulation in … spinal tissues after acute
traumatic spinal cord injury (ATSCI) are scarce. We aimed to identify lncRNA expression profiles …
traumatic spinal cord injury (ATSCI) are scarce. We aimed to identify lncRNA expression profiles …
[HTML][HTML] Specific blood RNA profiles in individuals with acute spinal cord injury as compared with trauma controls
Q Chen, L Wang, H Wu, C Ye, D Xie, Q Zhao… - … Medicine and Cellular …, 2023 - hindawi.com
… by various traffic accidents and violent injuries, spinal cord … , RNA-seq datasets related to
the spinal cord tissues and blood samples after acute SCI were used for bioinformatic analysis …
the spinal cord tissues and blood samples after acute SCI were used for bioinformatic analysis …
Signatures of altered long noncoding RNAs and messenger RNAs expression in the early acute phase of spinal cord injury
Z Shi, G Ning, B Zhang, S Yuan, H Zhou… - Journal of Cellular …, 2019 - Wiley Online Library
… To examine the dysregulated lncRNA expression signatures in injured spinal cord, we
analyzed upregulated and downregulated lncRNAs according length distribution and …
analyzed upregulated and downregulated lncRNAs according length distribution and …
[HTML][HTML] A transcriptomic meta-analysis shows lipid metabolism dysregulation as an early pathological mechanism in the spinal cord of SOD1 mice
LC Fernández-Beltrán, JM Godoy-Corchuelo… - International journal of …, 2021 - mdpi.com
… Many processes are implicated in the pathomechanism of ALS, including neuroinflammation,
RNA processing and metabolism, axonal transport, vesicle trafficking, proteostasis, …
RNA processing and metabolism, axonal transport, vesicle trafficking, proteostasis, …
[HTML][HTML] Gene expression analysis reveals early dysregulation of disease pathways and links Chmp7 to pathogenesis of spinal and bulbar muscular atrophy
… Our results show CHMP7 protein levels were decreased in the spinal cord of AR100 mice
prior to symptom onset and decreased further following symptom onset. LAMP2 and p62 were …
prior to symptom onset and decreased further following symptom onset. LAMP2 and p62 were …
[HTML][HTML] Buffy coat transcriptomic analysis reveals alterations in host cell protein synthesis and cell cycle in severe COVID-19 patients
LTF Cavalcante, GC da Fonseca… - International Journal of …, 2022 - mdpi.com
… analysis revealed 1009 up-regulated and 501 down-regulated genes in the SARS group,
with 10% of both being composed of long non-coding RNA. … enabling traffic of proteins, RNAs, …
with 10% of both being composed of long non-coding RNA. … enabling traffic of proteins, RNAs, …
[HTML][HTML] Single cell RNA-sequence analyses reveal uniquely expressed genes and heterogeneous immune cell involvement in the rat model of intervertebral disc …
… transcriptionally profiled at the single-cell resolution. Unsupervised cluster analysis revealed
… Differential gene expression analysis revealed multiple distinct cell types from the myeloid …
… Differential gene expression analysis revealed multiple distinct cell types from the myeloid …
[HTML][HTML] Single-cell analyses reveal the dynamic functions of Itgb2+ microglia subclusters at different stages of cerebral ischemia-reperfusion injury in transient middle …
F Zeng, J Cao, Z Hong, Y Liu, J Hao, Z Qin… - Frontiers in …, 2023 - frontiersin.org
Frontiers | Single-cell analyses reveal the dynamic functions of Itgb2+ microglia subclusters
at different stages of cerebral ischemia-reperfusion injury in transient middle cerebral …
at different stages of cerebral ischemia-reperfusion injury in transient middle cerebral …
[HTML][HTML] Ageing transcriptome meta-analysis reveals similarities and differences between key mammalian tissues
D Palmer, F Fabris, A Doherty, AA Freitas… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
… analysis and machine learning to functionally describe these signatures, revealing …
Further analyses revealed little overlap between genes differentially expressed with age in …
Further analyses revealed little overlap between genes differentially expressed with age in …
[HTML][HTML] Single-cell RNA sequencing reveals time-and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain
… and trafficking and has been implicated in AD pathophysiology 30 . Our analyses revealed
that … This analysis revealed associations between transcriptional signatures of distinct mouse …
that … This analysis revealed associations between transcriptional signatures of distinct mouse …