… of sphingolipid synthesis, and they account for much of the diversity in the sphingolipid class…
ER), including the sterol sensor SCAP and its partners insulin-induced gene-1 (INSIG1) and …

… Based on these observations and the potential of sterol-sphingolipid co-regulation, we
hypothesized that reducing sterol formation might suppress css1-3 by decreasing …

… We mainly focused on the lipid classes of sphingolipids and sterols and found that
sphingolipids Cer(d18:0/18:0), Cer(t18:0/22:0), Cer(d18:2/16:0), and Cer(d18:1/16:0) were …

… how sphingolipid species are affected in the brain of clinically advanced Huntington’s cases.
Sphingolipids … The caudate, putamen and cerebellum had distinct sphingolipid changes in …

… Moreover, lipidomic analysis of azole-resistant isolates has revealed alterations in both
sterols and sphingolipids, key membrane components that regulate membrane fluidity and …

… units of all sphingolipids, in … sphingolipids in PD is an increase in ceramide levels 46,47,48
. Due to their bioactive role within cell membranes sphingolipids are strongly linked to sterol …

… between membrane ergosterols and sphingolipids or alteration in … highlighted the role of
sphingolipid molecules as potential … Sterols were then extracted with a mixture of sterile distilled …

… With the extensive literature on the sterol biosynthetic pathway lacking evidence for sterol-…
in the sphingolipid synthesis pathway. We disrupted the de novo sphingolipid biosynthesis …

… sphingolipids in the lipid membrane of cells play important roles in various cellular processes.
However, the functions of sphingolipids … analysis of the sphingolipid synthesis pathway in …

… sphingolipids are strongly linked to sterol metabolism pathways and have an established
role in the modulation of steroidogenesis. There is a direct link between ceramides and the …