Structure, regulation, and biological functions of TIGAR and its role in diseases
… In 2006, Bensad cloned and identified the c12orf5 gene and named it TP53-induced
glycolysis and apoptosis regulator (TIGAR), reflecting its important role in maintaining the steady …
glycolysis and apoptosis regulator (TIGAR), reflecting its important role in maintaining the steady …
Receptor based virtual screening of potential novel inhibitors of tigar [TP53 (tumour protein 53)-induced glycolysis and apoptosis regulator
… Further, the molecular dynamics simulation studies indicated the structural stability
attained by TIGAR protein upon the binding of DDFA, suggesting it to be a potent inhibitor of …
attained by TIGAR protein upon the binding of DDFA, suggesting it to be a potent inhibitor of …
Molecular cloning and modeling of the Tp53-induced glycolysis and apoptotic regulator (TIGAR) from the Pacific white shrimp Litopenaeus vannamei and its …
L Camacho-Jiménez, M Felix-Portillo… - Fish & Shellfish …, 2019 - Elsevier
… Hypoxia-tolerant animals have developed biochemical and molecular strategies to survive
sub-… the Tp53-induced glycolysis and apoptotic regulator (TIGAR), a protein with structural …
sub-… the Tp53-induced glycolysis and apoptotic regulator (TIGAR), a protein with structural …
… of dioscin against hepatocellular carcinoma through regulating TP53‐induced glycolysis and apoptosis regulator (TIGAR)‐mediated apoptosis, autophagy, and DNA …
Z Mao, X Han, D Chen, Y Xu, L Xu, L Yin… - British journal of …, 2019 - Wiley Online Library
… in biosynthetic process, anatomical structure development, cellular nitrogen compound …
regulation associated with multiple genes, multiple signal pathways, and multiple biological …
regulation associated with multiple genes, multiple signal pathways, and multiple biological …
In silico identification of potential inhibitor for TP53-induced glycolysis and apoptosis regulator in head and neck squamous cell carcinoma
V Chandel, PP Sharma, SA Nayar, NK Jha, SK Jha… - 3 Biotech, 2021 - Springer
… mutated TP53-induced glycolysis and apoptosis regulator (TIGAR) … TIGAR plays an important
role in various biological … , 3D structure of TIGAR was compared with mutated TIGAR (Fig. 2…
role in various biological … , 3D structure of TIGAR was compared with mutated TIGAR (Fig. 2…
Knockdown of the TP53-induced glycolysis and apoptosis regulator (TIGAR) sensitizes glioma cells to hypoxia, irradiation and temozolomide
GD Maurer, S Heller, C Wanka, J Rieger… - International journal of …, 2019 - mdpi.com
… Underlining the potential biological relevance of TIGAR, treatment … analysis was not the
purpose of the present study. In order to gain an impression of the alterations induced by TIGAR …
purpose of the present study. In order to gain an impression of the alterations induced by TIGAR …
Immune landscape of hepatocellular carcinoma: The central role of TP53-inducible glycolysis and apoptosis regulator
L Qiu, T Ma, Y Guo, J Chen - Open Medicine, 2024 - degruyter.com
… -inducible glycolysis and apoptosis regulator (TIGAR) and … such as aromatase activity,
structural constituent of ribosome, … To deepen our understanding of TIGAR’s biological functions…
structural constituent of ribosome, … To deepen our understanding of TIGAR’s biological functions…
[图书][B] Investigation of the molecular basis for p53-mediated metabolic regulation in head and neck cancer
EAA Anaam - 2021 - search.proquest.com
… The functional regions in TIGAR gene structure Figure 1.10. Function of … A seminal
study in 2006 identified TP53-induced glycolysis and apoptosis regulator (TIGAR) as a novel …
study in 2006 identified TP53-induced glycolysis and apoptosis regulator (TIGAR) as a novel …
TP53, TP53 target genes (DRAM, TIGAR), and autophagy
W Hu, S Chen, RF Thorne, M Wu - … : Biology and Diseases: Basic Science, 2019 - Springer
… Numerous studies have now shown that the biological role of … TIGAR (TP53-induced
glycolysis and apoptosis regulator) is … into structural noncoding RNA (ncRNA) and regulatory …
glycolysis and apoptosis regulator) is … into structural noncoding RNA (ncRNA) and regulatory …
Inhibition of TIGAR Increases Exogenous p53 and Cisplatin Combination Sensitivity in Lung Cancer Cells by Regulating Glycolytic Flux
J Fu, S Yu, X Zhao, C Zhang, L Shen, Y Liu… - International Journal of …, 2022 - mdpi.com
… structure of the TIGAR is highly similar to the structural … The TP53-induced glycolysis and
apoptosis regulator (TIGAR… ; therefore, we speculate that the TIGAR may be a related factor in …
apoptosis regulator (TIGAR… ; therefore, we speculate that the TIGAR may be a related factor in …