[HTML][HTML] Nucleolin: a cell portal for viruses, bacteria, and toxins

F Tonello, ML Massimino, C Peggion - Cellular and Molecular Life …, 2022 - Springer
… characteristics that make nucleolin able to … nucleolin ability to interact with nucleic acids,
with proteins, but also with carbohydrates and lipids. This modular multivalence allows nucleolin

[HTML][HTML] Anti-nucleolin aptamer AS1411: an advancing therapeutic

A Van den Avont, N Sharma-Walia - Frontiers in Molecular …, 2023 - frontiersin.org
… Respiratory Syncytial Virus (RSV) has been shown to use nucleolin as a functional
receptor that passively interacts with fusion proteins (F proteins) (Figure 3). F proteins are …

Nucleolin-based targeting strategies for cancer therapy: from targeted drug delivery to cytotoxic ligands

S Romano, N Fonseca, S Simoes, J Goncalves… - Drug Discovery …, 2019 - Elsevier
… Similarly to what had been described for nucleolin and EGFR, combined treatment with
nucleolin and HER2 inhibitors revealed superior efficacy compared with single treatments in …

[HTML][HTML] Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation

SK Vester, RL Beavil, S Lynham, AJ Beavil… - Journal of Biological …, 2021 - ASBMB
nucleolin is mediated by the second C1q-like domain of C1QTNF4 and the C terminus of
nucleolin… Our results suggest that nucleolin may serve as a docking molecule for C1QTNF4 and …

Nucleolar protein nucleolin functions in replication stress–induced DNA damage responses

K Kawamura, F Qi, Q Meng, I Hayashi… - Journal of radiation …, 2019 - academic.oup.com
… that nucleolin plays an important role in IR-induced DSB damage responses [10]. We showed
that nucleolin … Furthermore, our results revealed that this functional activity of nucleolin was …

Nucleolin discriminates drastically between long-loop and short-loop quadruplexes

A Saha, P Duchambon, V Masson, D Loew… - Biochemistry, 2020 - ACS Publications
… We investigate herein the interaction between nucleolin (NCL) and a set of G4 sequences
derived from the CEB25 human minisatellite that adopt a parallel topology while differing in …

Exploring structural determinants and the role of nucleolin in formation of the long-range interactions between untranslated regions of p53 mRNA

A Kiliszek, W Rypniewski, L Błaszczyk - RNA, 2023 - rnajournal.cshlp.org
… This study explores structural determinants of long-range … We demonstrate that the 8-nt
bulge motif plays a key structural … of the p53 translation regulators, nucleolin, displays an RNA …

A novel role for nucleolin in splice site selection

K Shefer, A Boulos, V Gotea, M Arafat, Y Ben Chaim… - RNA biology, 2022 - Taylor & Francis
… Finally, upon nucleolin knockdown we show activation of latent splicing in hundreds of coding
transcripts having important cellular functions. We thus propose nucleolin, a component of …

[PDF][PDF] Nucleolin interacts and co-localizes with components of pre-catalytic spliceosome complexes

I Ugrinova, M Chalabi-Dchar, K Monier, P Bouvet - Sci, 2019 - researchgate.net
… from the nucleolin interacting proteins. Furthermore, we show that acetylated nucleolin co-…
P-SF3B1 complexes can be pulled down with nucleolin specific antibodies. Interestingly, …

Nucleolin‑based targeting strategies in cancer treatment: Focus on cancer immunotherapy

S Thongchot, K Aksonnam… - International …, 2023 - spandidos-publications.com
The benefits of treating several types of cancers using immunotherapy have recently been
established. The overexpression of nucleolin (NCL) in a number of types of cancer provides …