Genome-wide interaction study with major depression identifies novel variants associated with cognitive function

A Thalamuthu, NT Mills, K Berger, H Minnerup… - Molecular …, 2022 - nature.com
independent cohorts as part of the Cognitive Genomics Consortium (COGENT) found genetic
correlations between general … data found that MDD was genetically associated with slower …

Genetic mechanisms of cognitive development

RN Mustafin, AV Kazantseva, SB Malykh… - … Journal of Genetics, 2020 - Springer
… A study of 107 207 healthy individuals identified 70 independent genomic loci associated …
N = 300 486), the association of 709 genes with the g factor was confirmed. Moreover, novel …

GWAS of 19,629 individuals identifies novel genetic variants for regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits

B Zhao, T Luo, T Li, Y Li, J Zhang, Y Shan, X Wang… - bioRxiv, 2019 - biorxiv.org
… *10 −22 ) in the four independent studies can be explained by the … study identifies many new
genetic variants at SNP, locus and … genetic correlations linked 16 ROI volumes with general

General intelligence and executive functioning are overlapping but separable at genetic and molecular pathway levels: An analytical review of existing GWAS findings

LG Ciobanu, L Stankov, KO Schubert, AT Amare… - Plos one, 2022 - journals.plos.org
… 1,372 independent index g SNPs we identifiedgenetic correlation between g and EF; in
our study, we provide a comprehensive overview of individual variants that have been identified

[PDF][PDF] The “Golden Age” of behavioral genetics?

E Charney - The Samuel DuBois Cook Center on Social …, 2021 - socialequity.duke.edu
… “Study of 300,486 individuals identifies 148 independent genetic loci influencing general
cognitive function.” Nat Commun 9 (1):2098. Davis, OS, LM Butcher, SJ Docherty, EL Meaburn, …

Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS

WJ Peyrot, AL Price - Nature genetics, 2021 - nature.com
study 4 progressed the research on genetic differences between disorders by comparing
individual-… We identified 196 independent loci with different allele frequencies among cases of …

The genetics of human ageing

D Melzer, LC Pilling, L Ferrucci - Nature Reviews Genetics, 2020 - nature.com
… to be replicated in independent samples. In reviewing ageing … Six genetic loci were identified
in both studies for longer … The largest recent genetic study of general cognitive function …

Population-based genome-wide association study of cognitive decline in older adults free of dementia: identification of a novel locus for the attention domain

MI Kamboh, KH Fan, Q Yan, JC Beer, BE Snitz… - Neurobiology of …, 2019 - Elsevier
… 300,000 subjects identified 148 loci for general cognitive function that explained 4.3% of
variance in general cognitive function (Davies et al., 2018). Although this number of loci seems …

Multivariate genome-wide association study of depression, cognition, and memory phenotypes and validation analysis identify 12 cross-ethnic variants

J Sun, W Wang, R Zhang, H Duan, X Tian, C Xu… - Translational …, 2022 - nature.com
… to different ethnic groups (cross-ethnicity generalizability), we further validated the top
variants in an independent UK Biobank (UKB) population to identify cross-ethnic associations. …

Genome-wide association study shows that executive functioning is influenced by GABAergic processes and is a neurocognitive genetic correlate of psychiatric …

AS Hatoum, CL Morrison, EC Mitchell, M Lam… - Biological …, 2023 - Elsevier
… These studies have primarily focused on general cognitive … ) and 299 independent (r 2 <
0.6) SNPs in 112 distinct loci that … In MAGMA, we identified 319 genes significantly associated …