Phasic dopamine responses to a food-predictive cue are suppressed by the glucagon-like peptide-1 receptor agonist Exendin-4

VR Konanur, TM Hsu, SE Kanoski, MR Hayes… - Physiology & …, 2020 - Elsevier
dopamine signaling in response to both primary food rewardsuppresses dopamine neuron
firing rate and inhibits phasic … -evoked phasic dopamine signaling may also be mediated by …

Dopamine neurons gate the intersection of cocaine use, decision making, and impulsivity

TJ Hynes, KM Hrelja, BA Hathaway… - Addiction …, 2021 - Wiley Online Library
… Cue- and cocaine-induced suppression of dopamine may lead to reward-deficient states …
we observe here may be mediate by activity of dopamine in both the striatum and the mPFC. …

[HTML][HTML] Dopamine, behavior, and addiction

RA Wise, CJ Jordan - Journal of biomedical science, 2021 - Springer
… “pacemaker firing”—of dopaminergic neurons mediates motivational arousal. Motivational
… In dopamine-intact animals, dopaminergic neurons burst-fire in response not just to rewards

[HTML][HTML] Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion

C Soares-Cunha, NAP de Vasconcelos… - Molecular …, 2020 - nature.com
… NAc projections in rewarded behaviors, these also mediate/signal … heterogeneous dopamine
neuronal subpopulations with … optical stimulation of D2-MSNs suppresses it [15]. Yet, recent …

The power of price compels you: behavioral economic insights into dopamine-based valuation of rewarding and aversively motivated behavior

EB Oleson, JB Roberts - Brain research, 2019 - Elsevier
dopamine appears to mediate many … dopamine neurons fire in phasic bursts when animals
are presented with an unexpected reward or a reward predictive stimulus but are suppressed

[HTML][HTML] The cost of obtaining rewards enhances the reward prediction error signal of midbrain dopamine neurons

S Tanaka, JP O'Doherty, M Sakagami - Nature communications, 2019 - nature.com
dopamine neurons were found to show phasic activation and suppression to reward and no
reward… that RPEs are directly involved in mediating stimulus-reward learning, we expected …

Cannabinoids and the endocannabinoid system in reward processing and addiction: from mechanisms to interventions

R Spanagel - Dialogues in clinical neuroscience, 2020 - Taylor & Francis
suppression results in disinhibition of dopamine neurons, … that are involved in mediating
natural-reward and drug-seeking … area (VTA) A10 dopamine neurons by cannabinoid type 1 (…

Prefrontal cortical and nucleus accumbens contributions to discriminative conditioned suppression of reward-seeking

PT Piantadosi, DCM Yeates, SB Floresco - Learning & Memory, 2020 - learnmem.cshlp.org
… These findings extend our knowledge of cortico-striatal circuits mediating flexible reward-seeking,
identifying prefrontal input to the medial NAc as a critical component of such a network…

Impact of brain insulin signaling on dopamine function, food intake, reward, and emotional behavior

A Kleinridders, EN Pothos - Current nutrition reports, 2019 - Springer
… , dopaminergic neurons in the VTA modulate reward-related … Hypothalamic and striatal
insulin action suppresses … on increasing insulin-mediated suppression of endogenous glucose …

[PDF][PDF] Activation of the rostral intralaminar thalamus drives reinforcement through striatal dopamine release

KK Cover, U Gyawali, WG Kerkhoff, MH Patton, C Mu… - Cell reports, 2019 - cell.com
… release mechanisms in mediating reward-related behaviors. … receptor hM4Di-mediated
suppression of glutamate release from … oPSC events in medium spiny neurons (MSNs) in acute …