… bioactive substances … grapefruit pulp and two isolated compounds of grapefruit naringin
and limonin were studied against azomethane (AOM)-induced aberrant crypt foci in colon cancer…

… This review summarizes the main bioactive compounds against the molecular pathways
related to colorectal carcinogenesis. Moreover, we focus on the compounds with …

… Fruits contain major biologically active substances that are both … that the removal of these
key compounds either by … Apart from this, we have also demonstrated colon cancer cell …

… induce apoptosis in cancer cells [68], suppress the release of a … concern its possible role in
grapefruit juice–drug interactions [… in HT-29 colon cancer and MCF-7 breast cancer cells [98]. …

… found to be the major components in the citrus peel extracts of grapefruit, pomelo, kumquat,
… , inducing cell cycle arrest, and the apoptosis of HCT116 human colorectal cancer cells. …

… In addition, it was observed that it occurs a change in the composition of the gut microbiota
(dysbiosis) for people suffering from colorectal cancer or chronic inflammatory bowel disease […

… and bioactive compounds.3 A recent review stated that the bioactive compounds of grapefruit
… Delphinidin-3-glucoside (compound 1) has been extensively studied as a suppressive …

… The complex mixtures of bioactive compounds in plants … interaction of grapefruit is widely
known with anti-cancer and anti-… The current study, which was motivated by the “grapefruit (GF…

… natural carriers of bioactive compounds, suggesting their … cancer cells and represent a
promising therapeutic target [5]. Our data prove that NVs and MVs from grapefruit juice suppress …

… bioactive compounds have been isolated and characterized in GF. The abundance of these
compounds … Thus, GFJ improved glucose intolerance in diabetic rats by suppressing hepatic …