Permeation enhancers in transdermal drug delivery: Benefits and limitations

A Kováčik, M Kopečná, K Vávrová - Expert opinion on drug delivery, 2020 - Taylor & Francis
… We intentionally do not create separate groups for surfactants (all surfactants are
amphiphiles, either synthetic or semi-synthetic, and have various functional groups) or terpenes. …

[HTML][HTML] Improved topical drug delivery: Role of permeation enhancers and advanced approaches

V Hmingthansanga, N Singh, S Banerjee, S Manickam… - Pharmaceutics, 2022 - mdpi.com
… It comprises phospholipids, surfactants, and a higher amount of ethanol … in transdermal
drug delivery as a permeation enhancer to increase the transport of various drugs across the skin

[HTML][HTML] Current status of amino acid-based permeation enhancers in transdermal drug delivery

R Pereira, SG Silva, M Pinheiro, S Reis, ML Vale - Membranes, 2021 - mdpi.com
… Due to their physicochemical properties and self-assembling behavior, amino acid-based
gemini surfactants can be used as skin permeation enhancers as well as drug delivery

[PDF][PDF] Drug penetration enhancement techniques in transdermal drug delivery system: A review

JH Anantrao, PA Nath, PR Nivrutti - J. Pharm. Res. Int, 2021 - pdfs.semanticscholar.org
… of transdermal or topical drug delivery system from the skin. 5. The penetration enhancers
… The anionic and cationic surfactants can cause to damage human skin [40]. Sodium lauryl …

Non-ionic surfactants as innovative skin penetration enhancers: Insight in the mechanism of interaction with simple 2D stratum corneum model system

F Strati, RHH Neubert, L Opálka, A Kerth… - … of Pharmaceutical …, 2021 - Elsevier
… , 1998, Kiss, 2014) emulsifiers or skin conditioners. The objective of this study was to show
the potential of NIS as non-toxic skin penetration enhancers for transdermal drug delivery. …

Natural Ingredients of Transdermal Drug Delivery Systems as Permeation Enhancers of Active Substances through the Stratum Corneum

N Schafer, R Balwierz, P Biernat… - Molecular …, 2023 - ACS Publications
… In an in vitro study, a gel with 10% urea increased transdermal caffeine delivery by almost
50%, at a level similar to the permeation-enhancing effect of the surfactant sodium laureth …

[HTML][HTML] Ionic liquids as potential and synergistic permeation enhancers for transdermal drug delivery

Z Sidat, T Marimuthu, P Kumar, LC du Toit… - Pharmaceutics, 2019 - mdpi.com
Surfactants are versatile and relatively safe and are, therefore, … permeation enhancement
effects; however, the most active permeation surfactants are also extremely irritant to the skin

Topical drug delivery therapeutics, drug absorption and penetration enhancement techniques

KS Bani, K Bhardwaj - Journal of Drug Delivery and Therapeutics, 2021 - jddtonline.info
… the drug's pharmacological or other effect to the skin's surface or within the skin is referred
to as topical drug delivery. Topical action may or may not require intracutaneous injections.…

Hydrogels for dermal and transdermal drug delivery

H Labie, M Blanzat - Biomaterials Science, 2023 - pubs.rsc.org
… nanoparticles – suitable for skin penetration enhancement and drug protection, as well as
… , and the oil and surfactant used can act as chemical permeation enhancers. Emulgels can …

Overcoming skin barriers through advanced transdermal drug delivery approaches

V Phatale, KK Vaiphei, S Jha, D Patil, M Agrawal… - … of controlled release, 2022 - Elsevier
… The available permeation enhancers increase transdermal drug absorption by dissolving the
skin lipid or … Although, the permeation enhancement mechanism of surfactant often leads to …