Antitumoral effects of tricyclic antidepressants: Beyond neuropathic pain treatment

A Asensi-Cantó, MD López-Abellán… - Cancers, 2022 - mdpi.com
… of antidepressants on the overall survival of the studied cohort of lung cancer patients [129]. …
TCAs translated to improved survival in patients with colorectal cancer or glioma showed no …

Impact of polypharmacy for chronic ailments in colon cancer patients: a review focused on drug repurposing

R Giampieri, L Cantini, E Giglio, A Bittoni, A Lanese… - Cancers, 2020 - mdpi.com
… prevention of both colorectal cancer and glioma. The same group of authors in a following
paper [73] assessed the survival of CRC patients who used TCAs post-diagnosis: the authors …

Depression and quality of life in patients with gliomas: a narrative review

Y Hu, F Deng, L Zhang, K Hu, S Liu, S Zhong… - Journal of Clinical …, 2022 - mdpi.com
… with shorter survival in patients with gliomas, and patients with gliomas with … antidepressant
use on the risk of glioma [85,86]. Tricyclic antidepressants (TCAs) reduce the risk of glioma

[PDF][PDF] Adherence to antidepressant medications is associated with reduced premature mortality in patients with cancer: A nationwide cohort study

I Aviv - kclpure.kcl.ac.uk
patients with either colorectal cancer or glioma, there was no significant mortality reduction
in those who used tricyclic antidepressants (… with increased survival in patients with cancer, …

[HTML][HTML] Antidepressant use and colorectal cancer morbidity and mortality: a dose-response meta analysis

L Chen, X Li, C Li, C Zou - Medicine, 2020 - journals.lww.com
survival rate of colorectal liver metastases patients after surgical resection is up to 50%, but
only 20% of patients … inhibitor (SNRI) and tricyclic antidepressant (TCA) treat depression. The …

[HTML][HTML] Pharmacological treatment of depression in people with a primary brain tumour

Z Beevers, S Hussain, FW Boele… - The Cochrane Database …, 2020 - ncbi.nlm.nih.gov
… of using tricyclic antidepressants for mortality reduction in people with glioma or colorectal
cancer. … , examining the relationship between depression and survival in glioma. However, the …

[HTML][HTML] Psychotropic drugs show anticancer activity by disrupting mitochondrial and lysosomal function

M Varalda, A Antona, V Bettio, K Roy… - … in oncology, 2020 - frontiersin.org
… in colorectal carcinoma, glioblastoma and breast cancer cell … restricted to colorectal cancer
and breast cancer and caused … tumors are highly dependent on autophagy for survival and …

… approach reveals role of mitochondrial germ-line mutation F18L in respiratory chain, oxidative alterations, drug sensitivity, and patient prognosis in glioblastoma

K Keatley, S Stromei-Cleroux, T Wiltshire… - International journal of …, 2019 - mdpi.com
survival for glioblastoma patients well enough to receive the standard of care treatment is just
14.6 months post-diagnosis … Clomipramine is a tricyclic antidepressant drug that is effective …

[HTML][HTML] A systematic review of pharmacologic treatment efficacy for depression in older patients with cancer

EE Rabin, M Kim, A Mozny, K Cardoza, AC Bell… - Brain, Behavior, & …, 2022 - Elsevier
… , 2 publications included serotonin and norepinephrine reuptake inhibitors (SNRIs), 5
publications included tricyclic antidepressants (TCAs), and 7 publications included other atypical …

Review of pharmacological treatment of depression in patients with primary brain tumour and proposal of modification in management strategy

OK Onyia, CU Onyia - Clinical Neurology and Neurosurgery, 2022 - Elsevier
… worsen overall survival and prognosis in patients with brain … inhibitors (SSRIs), the tricyclic
antidepressants (TCA) and the … of using TCAs for patients with glioma or colorectal cancer. …