Left ventricular remodeling after myocardial infarction: from physiopathology to treatment

SA Leancă, D Crișu, AO Petriș, I Afrăsânie, A Genes… - Life, 2022 - mdpi.com
… In this phase, initial myocardial deformation by the persistent stretching of the myocytes …
MI, as it regulates and promotes LV collagen deposition, cardiomyocyte apoptosis, endothelial …

Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies

S Frantz, MJ Hundertmark… - European heart …, 2022 - academic.oup.com
Left: Persistent increase of afterload, and subsequently … tissue formation and progressive
cardiomyocyte death. Chronic … HF development, adverse remodelling and cell death in murine …

Necroptosis mediated by impaired autophagy flux contributes to adverse ventricular remodeling after myocardial infarction

H Zhang, Y Yin, Y Liu, G Zou, H Huang, P Qian… - Biochemical …, 2020 - Elsevier
cardiomyocytes by cell death after myocardial infarction is … left ventricular remodeling, cardiac
dysfunction and heart failure. … with sustained loss of cardiomyocytes by cell death accounts …

The relevance of microRNA in post-infarction left ventricular remodelling and heart failure

M Dutka, R Bobiński, J Korbecki - Heart failure reviews, 2019 - Springer
left ventricular remodelling following a myocardial infarction. New … who had suffered an acute
myocardial infarction than in … cardiomyocyte apoptosis, left ventricular remodelling and left

Myocardial injury, troponin release, and cardiomyocyte death in brief ischemia, failure, and ventricular remodeling

JM Canty Jr - American Journal of Physiology-Heart and …, 2022 - journals.physiology.org
… In acute myocardial infarction, necrotic cell death is … In these studies, a persistent increase
in myocyte apoptosis … hypertension, or postinfarction left ventricular remodeling. This may …

[HTML][HTML] Proline improves cardiac remodeling following myocardial infarction and attenuates cardiomyocyte apoptosis via redox regulation

J Wang, Z Xue, J Lin, Y Wang, H Ying, Q Lv… - Biochemical …, 2020 - Elsevier
… was maintained at 37 C with a heating pad, and the heart rate was maintained at
approximately 500 beats min −1 . The left ventricle ejection fraction (LVEF), left ventricle fractional …

Unresolved issues in left ventricular postischemic remodeling and progression to heart failure

E Gronda, S Sacchi, G Benincasa… - Journal of …, 2019 - journals.lww.com
… In the past decades, myocardial infarction periacute mortality … and apoptosis in the negative
remodeling process after a MI. The … Vascular remodeling is a constant pathogenic event in …

Cardiomyocytes cellular phenotypes after myocardial infarction

AM Lodrini, MJ Goumans - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
… This late onset of apoptosis is then sustained during the chronic phase of ischemia and …
after left coronary artery (LCA) ligation. Of note, apoptosis after MI is mostly present in the infarct

Insight into the role of the PI3K/Akt pathway in ischemic injury and post-infarct left ventricular remodeling in normal and diabetic heart

B Walkowski, M Kleibert, M Majka, M Wojciechowska - Cells, 2022 - mdpi.com
… of myocardial infarction and the post-infarction remodeling of the … As a constant supply
of blood to cardiomyocytes is of … the apoptosis rate of cardiomyocytes and induces cardiac

Pharmacological modulation of cardiac remodeling after myocardial infarction

W Zhao, J Zhao, J Rong - Oxidative Medicine and Cellular …, 2020 - Wiley Online Library
… of the chronic phase of left ventricular remodeling [14, 15]. It … The sustained release of
angiotensin promotes cardiac … and cardiomyocyte apoptosis in the infarcted myocardium [107]. …