… underlying the synergistic effect of the combination of CAR-T cells and IL-12, we performed
… independent parameters representing lineage and activation markers (Supplementary Table …

… , combined treatment with IL-7 and IL-12 promoted the activation of CD8+ T cells, which
had a better effect on CD8+ T cell activation than the control group expressing IL-12 alone. …

… TCR stimulation and IL-27 resulted in synergistic induction of … by murine CD4 + T cells (15)
and the ability of IL-2, IL-7, IL-15, … IL-27 is an IL-6/IL-12 family cytokine that signals through …

… Given the potent functional effects induced by the combined stimulation of IL-12, -15, and -…
would be beneficial for generating ML NK cells for both research and clinical applications. As …

… , find a synergistic effect between TGF-β and IL-12 or IL-23 … CD4 T cells compared with T reg
cells after exposure to IL-12, … cytokine combinations above with interleukin-7 (IL-7) (4 ng/ml) …

… ), IL-8, IL-12, and IL-23 upon activation with interferon-γ (IFNγ), … IFNγ produced by the
synergistic effect of LPS and IL-7, which … We also conclude that T cells participate in IL-7-induced …

… IL-12 expression alone. In addition, the combination of IL-7 and IL-12 could synergistically
stimulate T cells … states, and enhance anti-tumor effects. In addition, the combination of these …

… test whether the synergistic effect seen was mediated … IL-7 treatment also reversed the
MAIT cell effector dysfunction seen in HIV infected patients 28. IL-7 can also synergise with IL-12 …

… of human CD8 + MAIT cells to TCR and cytokine stimulation. We report that MAIT cells
rapidly respond to TCR stimulation, … The synergy between TCR signals and cytokine-mediated …

… T-cells. While various preclinical studies have evaluated a plethora of cytokines: Il-7, IL-15,
IL-12, IL-18, and their role in enhancing the functional survival and persistence of T-cells in …