… -21, IL-7 have been reported to play a synergistic and unique … confirmed and includes IL-4,
IL-7, IL-9, IL-12, and IL-21 (20). … -2, IL-7 can accelerate the proliferation of T cells expressing …

… IL-12 and IL-18 synergistically enhance CTL and NK cell … Cryopreserved CTL avatars were
thawed and rested in cRPMI with IL-7 … of IL-12 and IL-18 in combination promote CD4 + T cell …

… As with IL-12, IL-18 activates Th1 and NK cells to release pro-… to the IL-7 intracellular
domain so that on stimulation of CAR T-… Citation78 The synergistic effect of CAR T-cells with …

… T cell activation is induced when tumor antigens are … antibodies with Local IL-12 can realize
synergistic results to … to found cytokine-based drugs with a synergistic effect with PD-1/PD-L1 …

… to cytokines, such as interleukin (IL)–2, IL-4, and IL-7, induces … establish that STAT5 activation
downstream of IL-12 and the … in red, are indicative of a synergistic interaction. Statistical …

… IL-35 is a newly identified IL-12 cytokine family member, and … virus-induced gene 3 (EBI3)
and IL-12 α chain p35 (IL-12p35). … IL-1, IL-7, IL-21, and IL-25, were identified to synergistically …

… vectors (NV1042) exhibited additive or synergistic effects on prostate cancer cell lines [46].
The … expression of IL-7 and IL-12 in tumors increased the number of activated CD8 + T cells in …

… the synergistic effect of IL-7 and CCL19, 7 × 19 CAR T cells … , IL-12 released by CAR T cells
also activated cytolytic T cells and natural killer cells, while inhibiting the function of Treg cells…

… memory CD8 + T cells; however, the expression of the IL-7 receptor alone … signaling of IL-7
and IL-15 synergistically fosters the … that IL-12 enhances the expansion of CD8 + T cells and …

… Here, we summarize the numerous challenges faced by CAR T-cells designed to target …
posit strategies for the synergistic combination of oncolytic viruses with CAR T-cells to improve …