[HTML][HTML] Immunological effects and viral gene expression determine the efficacy of oncolytic measles vaccines encoding IL-12 or IL-15 agonists
…, JE Dunder, LM Jeworowski, J Albert, B Hoyler, T Poth… - Viruses, 2019 - mdpi.com
… over IL-12 as it does not stimulate regulatory T cell function and inhibits the induction of AICD
[20,21,22,23,24]. This effect … An NDV variant encoding both IL-15 and IL-7 developed as a …
[20,21,22,23,24]. This effect … An NDV variant encoding both IL-15 and IL-7 developed as a …
[HTML][HTML] Regulation of osteoblast differentiation by cytokine networks
DS Amarasekara, S Kim, J Rho - International journal of molecular …, 2021 - mdpi.com
… IL-7 is a crucial cytokine in B and T cell lymphopoiesis [148]. It has … Moreover, IL-12 and
IL-23 indirectly inhibit … Furthermore, IL-17 exhibits synergistic effects with BMP-2 in matrix …
IL-23 indirectly inhibit … Furthermore, IL-17 exhibits synergistic effects with BMP-2 in matrix …
[HTML][HTML] Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis
… IL-7 was added to the culture medium for T-cell survival and maintenance 28,29 . Consistent
with previous results 30,31 , we found that IL-12 … + T cells, which showed a synergistic effect …
with previous results 30,31 , we found that IL-12 … + T cells, which showed a synergistic effect …
[HTML][HTML] Cytokines in oncolytic virotherapy
Tumors represent a hostile environment for the effector cells of cancer immunosurveillance.
Immunosuppressive receptors and soluble or membrane-bound ligands are abundantly …
Immunosuppressive receptors and soluble or membrane-bound ligands are abundantly …
Cytokines in type 1 diabetes: mechanisms of action and immunotherapeutic targets
J Lu, J Liu, L Li, Y Lan, Y Liang - Clinical & translational …, 2020 - Wiley Online Library
… Th17 cells Increasing islet-infiltrating CD4 + T cells IL-12 had a dual role in T1D None IL-7 …
may have a synergistic effect on the preservation of β-cell function by reducing local β-…
may have a synergistic effect on the preservation of β-cell function by reducing local β-…
[HTML][HTML] Analysis and augmentation of the immunologic bystander effects of CAR T cell therapy in a syngeneic mouse cancer model
A Klampatsa, MS Leibowitz, J Sun, M Liousia… - Molecular Therapy …, 2020 - cell.com
… times per week) had a synergistic effect with M11 CAR T cells and stopped tumor growth; …
CAR T cells) had no effect, either as a single agent or in combination with M11 CAR T cells. (E) …
CAR T cells) had no effect, either as a single agent or in combination with M11 CAR T cells. (E) …
Relaxin-FOLFOX-IL-12 triple combination therapy engages memory response and achieves long-term survival in colorectal cancer liver metastasis
… The autocrine maturation and activation of DCs by IL-12 was … The triple combinational
treatment further synergistically … as IL-7 and IL-15 also have a fundamental role in T cell clonal …
treatment further synergistically … as IL-7 and IL-15 also have a fundamental role in T cell clonal …
Immune-enhancing effects of glucocorticoids in response to day–night cycles and stress
A Shimba, K Ikuta - International Immunology, 2020 - academic.oup.com
… IL-12 and IL-18 production from antigen-presenting cells, … A synergistic effect of GR and the
IL-7R signal enhances IL-… IL-7R is highly expressed on memory T cells, and the IL-7 signal is …
IL-7R signal enhances IL-… IL-7R is highly expressed on memory T cells, and the IL-7 signal is …
[HTML][HTML] Intratumoral IL-12 delivery via mesenchymal stem cells combined with PD-1 blockade leads to long-term antitumor immunity in a mouse glioblastoma model
… S1), the synergistic association between MSCs and their … IL-12 mainly increased tumor
infiltration of CD4 + T cells and NK cells, while anti-PD-1 mainly increased that of CD8 + T cells. …
infiltration of CD4 + T cells and NK cells, while anti-PD-1 mainly increased that of CD8 + T cells. …
[HTML][HTML] Effect of sishen pill on memory T cells from experimental colitis induced by dextran sulfate sodium
W Ge, HY Wang, HM Zhao, XK Liu, YB Zhong… - Frontiers in …, 2020 - frontiersin.org
… )-2 and IL-7, PI3K/Akt signal activation can regulate the differentiation … IL-12 can promote the
transformation of CD8 + T cells into … The synergistic effect of T-bet and eomesodermin could …
transformation of CD8 + T cells into … The synergistic effect of T-bet and eomesodermin could …