Synthesis of Oligonucleotides Containing the N6‐(2‐Deoxy‐α,β‐d‐erythropentofuranosyl)‐2,6‐diamino‐4‐hydroxy‐5‐formamidopyrimidine (Fapy⋅dG) Oxidative …
… difficulty in synthesizing oligonucleotides containing Fapy⋅dG … approach for preparing
oligonucleotides containing Fapy⋅… of oligonucleotides as long as 30 nucleotides are synthesized. …
oligonucleotides containing Fapy⋅… of oligonucleotides as long as 30 nucleotides are synthesized. …
Oligonucleotides Containing 1-Aminomethyl or 1-Mercaptomethyl-2-deoxy-d-ribofuranoses: Synthesis, Purification, Characterization, and Conjugation with …
… The synthetic protocol for the 1-S-mercaptomethyl-1,2-dideoxy-d-erythro-pentofuranosyl-3-O-phosphoramidites
16α or 16β is summarized in Scheme 3. The nitriles 1α/1β were treated …
16α or 16β is summarized in Scheme 3. The nitriles 1α/1β were treated …
7‐(β‐D‐Ribofuranosyl)guanine and its Analogues Modified in the Sugar Portion: Synthesis and Antiglioma Properties
D Wawrzyniak, G Framski, P Januszczyk… - …, 2020 - Wiley Online Library
… to incorporate the 7-nucleosides into oligonucleotides has … -pentofuranosyl) anomer (21)
(Figure 2) were isolated as … -O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)-N 2 -acetylguanine, …
(Figure 2) were isolated as … -O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)-N 2 -acetylguanine, …
[HTML][HTML] Recent advances in the chemical synthesis and evaluation of anticancer nucleoside analogues
… Herein, we discuss recent advances in the chemical synthesis and biological evaluation
of nucleoside analogues as potential anticancer agents. Focus is paid to 4′-heteroatom …
of nucleoside analogues as potential anticancer agents. Focus is paid to 4′-heteroatom …
3 Synthesis of oligonucleotides carrying modified bases for DNA and protein recognition
… The synthesis of oligonucleotides carrying mutagenic bases … Oligonucleotides carrying
mutagenic DNA lesions have … In this chapter, we will detail the synthesis of oligonucleotides …
mutagenic DNA lesions have … In this chapter, we will detail the synthesis of oligonucleotides …
[HTML][HTML] Cationic oligonucleotide derivatives and conjugates: A favorable approach for enhanced DNA and RNA targeting oligonucleotides
MB Danielsen, J Wengel - Beilstein Journal of Organic …, 2021 - beilstein-journals.org
… In this review, we focus on important monomeric cationic modifications for ASOs, including
locked nucleic acid (LNA) monomers, and their synthesis. Such modifications have been …
locked nucleic acid (LNA) monomers, and their synthesis. Such modifications have been …
2 Synthesis of oligonucleotides carrying DNA lesions for DNA repair studies
… without using ammonia and its application for the synthesis of oligonucleotides containing
O -4-alkyl … Synthesis and properties of oligonucleotides containing the mutagenic base O4 -…
O -4-alkyl … Synthesis and properties of oligonucleotides containing the mutagenic base O4 -…
Gapmer Antisense Oligonucleotides Containing 2′,3′‐Dideoxy‐2′‐fluoro‐3′‐C‐hydroxymethyl‐β‐d‐lyxofuranosyl Nucleotides Display Site‐Specific RNase H …
MB Danielsen, C Lou… - … A European Journal, 2020 - Wiley Online Library
… C (Figure 1) having a 2′,3′-dideoxy-2′-fluoro-3′-C-hydroxymethyl-β-d-lyxofuranosyl
constitution. In the present study, we describe the synthesis of the uracil and cytosine …
constitution. In the present study, we describe the synthesis of the uracil and cytosine …
Nucleobase-Functionalized 5-Aza-7-deazaguanine Ribo-and 2′-Deoxyribonucleosides: Glycosylation, Pd-Assisted Cross-Coupling, and Photophysical Properties
P Leonard, D Kondhare, X Jentgens… - The Journal of …, 2019 - ACS Publications
… and oligonucleotides with imidazo[1,2-a]-s-triazines (5-aza-7-deazapurines) as base having
the … Following the literature procedure for the preparation of 10b, we were encountered with …
the … Following the literature procedure for the preparation of 10b, we were encountered with …
Recent Advances in the Synthesis of 5′-deoxynucleoside Phosphonate Analogs
GH Shen, JH Hong - Current Medicinal Chemistry, 2022 - ingentaconnect.com
… Abstract: The present review focuses on the synthesis of cyclic 5′-deoxynucleoside …
phosphonate linked thymidine oligonucleotides [37]. The preparation of the unsaturated …
phosphonate linked thymidine oligonucleotides [37]. The preparation of the unsaturated …